Morphology Control of Self-Assembled Copper Coordination Polymers for Glucose Assays

Low-cost analytical assays enable accessible detection of clinically and environmentally important analytes; however, common enzyme-based assays suffer from high production and storage costs. Catalytically active synthetic materials serve as replacements for natural enzymes, but development of cost-...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - (2024) vom: 06. Feb.
1. Verfasser: Van Houten, Justin (VerfasserIn)
Weitere Verfasser: Dosajh, Advikaa, Gulati, Shriya, Bhullar, Gurjap, Copeman, Christopher, Ogata, Alana F
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2024
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article
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520 |a Low-cost analytical assays enable accessible detection of clinically and environmentally important analytes; however, common enzyme-based assays suffer from high production and storage costs. Catalytically active synthetic materials serve as replacements for natural enzymes, but development of cost-effective, highly efficient synthetic strategies remains a challenge. Here, we utilized a facile synthesis for copper bipyridine coordination polymers (CuBpyCPs) and investigated structure-function relationships to achieve optimal catalytic properties for a glucose assay. We demonstrated the manipulation of CuBpyCP morphology, resulting in nanoscale petal-like structures and microscale high-index faceted structures, and identified three pure crystal morphologies exhibiting a comparable catalytic activity (Km = 0.3-0.5 mM) to horseradish peroxidase 
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700 1 |a Gulati, Shriya  |e verfasserin  |4 aut 
700 1 |a Bhullar, Gurjap  |e verfasserin  |4 aut 
700 1 |a Copeman, Christopher  |e verfasserin  |4 aut 
700 1 |a Ogata, Alana F  |e verfasserin  |4 aut 
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