Quantitative Contrast Sensitivity Function and the Effect of Aging in Healthy Adult Eyes : A Normative Database

BACKGROUND AND OBJECTIVE: We sought to establish normative quantitative contrast sensitivity function (qCSF) values in healthy adult eyes and investigate the effect of age on qCSF

Bibliographische Detailangaben
Veröffentlicht in:Ophthalmic surgery, lasers & imaging retina. - 2013. - 55(2024), 4 vom: 01. Apr., Seite 212-219
1. Verfasser: Choi, Hanna (VerfasserIn)
Weitere Verfasser: Vingopoulos, Filippos, Razavi, Peyman, Garcia, Mauricio D, Garg, Itika, Rodriguez, Jocelyn, Finn, Matthew, Baldwin, Grace, Romano, Francesco, Ding, Xinyi, Bannerman, Augustine, Tracy, Jack, Wescott, Hannah, Husain, Deeba, Kim, Leo A, Vavvas, Demetrios G, Miller, John B
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2024
Zugriff auf das übergeordnete Werk:Ophthalmic surgery, lasers & imaging retina
Schlagworte:Journal Article Research Support, Non-U.S. Gov't
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100 1 |a Choi, Hanna  |e verfasserin  |4 aut 
245 1 0 |a Quantitative Contrast Sensitivity Function and the Effect of Aging in Healthy Adult Eyes  |b A Normative Database 
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500 |a Citation Status MEDLINE 
520 |a BACKGROUND AND OBJECTIVE: We sought to establish normative quantitative contrast sensitivity function (qCSF) values in healthy adult eyes and investigate the effect of age on qCSF 
520 |a PATIENTS AND METHODS: Healthy eyes underwent qCSF testing (adaptive sensory technology) and Snellen's visual acuity (VA). Descriptive statistics and mixed-effects multivariable linear regressions were evaluated 
520 |a RESULTS: A total of 334 eyes (290 patients) with median age 61 years (range 21 to 88) had qCSF values as follows: area under the log contrast sensitivity function curve: 1.18; contrast acuity: 1.32; contrast sensitivity (CS) at 1 cycle per degree (cpd): 1.32; CS at 1.5 cpd: 1.37; CS at 3 cpd: 1.38; CS at 6 cpd: 1.20; CS at 12 cpd: 0.69; CS at 18 cpd: 0.22. Linear reductions in qCSF values per decade of age ranged from -0.02 to -0.07 vs 0.01 for visual acuity (VA). Age had a greater effect on the majority of qCSF values than VA (beta standardized regression coefficient ranged from -0.309 to -0.141 for qCSF values vs 0.177 for VA) 
520 |a CONCLUSIONS: We herein establish a normative database for qCSF and quantify the effect of age on qCSF values, adding evidence towards the validation of qCSF as a clinical endpoint. [Ophthalmic Surg Lasers Imaging Retina 2024;55:212-219.] 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
700 1 |a Vingopoulos, Filippos  |e verfasserin  |4 aut 
700 1 |a Razavi, Peyman  |e verfasserin  |4 aut 
700 1 |a Garcia, Mauricio D  |e verfasserin  |4 aut 
700 1 |a Garg, Itika  |e verfasserin  |4 aut 
700 1 |a Rodriguez, Jocelyn  |e verfasserin  |4 aut 
700 1 |a Finn, Matthew  |e verfasserin  |4 aut 
700 1 |a Baldwin, Grace  |e verfasserin  |4 aut 
700 1 |a Romano, Francesco  |e verfasserin  |4 aut 
700 1 |a Ding, Xinyi  |e verfasserin  |4 aut 
700 1 |a Bannerman, Augustine  |e verfasserin  |4 aut 
700 1 |a Tracy, Jack  |e verfasserin  |4 aut 
700 1 |a Wescott, Hannah  |e verfasserin  |4 aut 
700 1 |a Husain, Deeba  |e verfasserin  |4 aut 
700 1 |a Kim, Leo A  |e verfasserin  |4 aut 
700 1 |a Vavvas, Demetrios G  |e verfasserin  |4 aut 
700 1 |a Miller, John B  |e verfasserin  |4 aut 
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773 1 8 |g volume:55  |g year:2024  |g number:4  |g day:01  |g month:04  |g pages:212-219 
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