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240119s2024 xx |||||o 00| ||eng c |
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|a 10.1002/adma.202310212
|2 doi
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|a pubmed24n1417.xml
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|a (DE-627)NLM367271583
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|a (NLM)38236647
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|a DE-627
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|e rakwb
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|a eng
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|a Chai, Huichao
|e verfasserin
|4 aut
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|a Capillarity Enabled Large-Array Liquid Metal Electrodes for Compact and High-Throughput Dielectrophoretic Microfluidics
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|c 2024
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|a Text
|b txt
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|a ƒaComputermedien
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|a ƒa Online-Ressource
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|a Date Revised 24.05.2024
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|a published: Print-Electronic
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|a Citation Status PubMed-not-MEDLINE
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|a © 2024 Wiley‐VCH GmbH.
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|a Dielectrophoresis (DEP) particle separation has label-free, well-controllable, and low-damage merits. Sidewall microelectrodes made of liquid metal alloy (LMA) inherits the additional advantage of thick electrodes to generate impactful DEP force. However, existing LMA electrode-based devices lack the ability to integrate large-array electrodes in a compact footprint, severely limiting flow rate and thus throughput. Herein, a facile and versatile method is proposed to integrate high-density thick LMA electrodes in microfluidic devices, taking advantage of the passive control ability of capillary burst valves (CBVs). CBVs with carefully designed burst pressures are co-designed in microfluidic channels, allowing self-assembly of LMA electrode array through simple hand-push injection. The arrayed electrode configuration brings the accumulative DEP deflection effect. Specifically, The fabricated 5000 pairs of sidewall electrodes in a compact chip are demonstrted to achieve ten times higher throughput in DEP deflection. The 5000-electrode-pair device is applied to successfully separate four mixed samples, including human peripheral blood mononuclear cells and A549 cells with the flow rate of 70 µL min-1. It is envisioned that this work can greatly facilitate LMA electrode array fabrication and offer a robust and versatile platform for DEP separation applications
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|a Journal Article
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|a capillarity
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|a dielectrophoresis
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|a large‐array electrodes
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|a liquid metal
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|a microfluidics
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1 |
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|a Zhu, Junwen
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Feng, Yongxiang
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Liang, Fei
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Wu, Qiyan
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Ju, Zhongjian
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Huang, Liang
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Wang, Wenhui
|e verfasserin
|4 aut
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| 773 |
0 |
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|i Enthalten in
|t Advanced materials (Deerfield Beach, Fla.)
|d 1998
|g 36(2024), 21 vom: 31. Mai, Seite e2310212
|w (DE-627)NLM098206397
|x 1521-4095
|7 nnns
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| 773 |
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|g volume:36
|g year:2024
|g number:21
|g day:31
|g month:05
|g pages:e2310212
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|u http://dx.doi.org/10.1002/adma.202310212
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