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231226s2024 xx |||||o 00| ||eng c |
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|a 10.1002/adma.202306669
|2 doi
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|a pubmed24n1295.xml
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|a (DE-627)NLM365537810
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|a (NLM)38062893
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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1 |
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|a Beckham, Jacob L
|e verfasserin
|4 aut
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| 245 |
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|a Distinguishing Molecular Mechanical Action from Photothermal and Photodynamic Behavior
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|c 2024
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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| 500 |
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|a Date Completed 16.02.2024
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|a Date Revised 16.02.2024
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2023 Wiley-VCH GmbH.
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|a Molecular motors (MM) are molecular machines, or nanomachines, that rotate unidirectionally upon photostimulation and perform mechanical work on their environment. In the last several years, it has been shown that the photomechanical action of MM can be used to permeabilize lipid bilayers, thereby killing cancer cells and pathogenic microorganisms and controlling cell signaling. The work contributes to a growing acknowledgement that the molecular actuation characteristic of these systems is useful for various applications in biology. However, the mechanical effects of molecular motion on biological materials are difficult to disentangle from photodynamic and photothermal action, which are also present when a light-absorbing fluorophore is irradiated with light. Here, an overview of the key methods used by various research groups to distinguish the effects of photomechanical, photodynamic, and photothermal action is provided. It is anticipated that this discussion will be helpful to the community seeking to use MM to develop new and distinctive medical technologies that result from mechanical disruption of biological materials
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|a Journal Article
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|a biological materials
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| 650 |
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|a molecular machines
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| 650 |
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|a photodynamic therapy
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|a photomechanical
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|a reactive oxygen species
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|a Lipid Bilayers
|2 NLM
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1 |
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|a Bradford, Thomas S
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Ayala-Orozco, Ciceron
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Santos, Ana L
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Arnold, Dallin
|e verfasserin
|4 aut
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| 700 |
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|a van Venrooy, Alexis R
|e verfasserin
|4 aut
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| 700 |
1 |
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|a García-López, Víctor
|e verfasserin
|4 aut
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| 700 |
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|a Pal, Robert
|e verfasserin
|4 aut
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| 700 |
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|a Tour, James M
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Advanced materials (Deerfield Beach, Fla.)
|d 1998
|g 36(2024), 7 vom: 07. Feb., Seite e2306669
|w (DE-627)NLM098206397
|x 1521-4095
|7 nnns
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| 773 |
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|g volume:36
|g year:2024
|g number:7
|g day:07
|g month:02
|g pages:e2306669
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|u http://dx.doi.org/10.1002/adma.202306669
|3 Volltext
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