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231226s2023 xx |||||o 00| ||eng c |
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|a 10.1021/acs.langmuir.3c02314
|2 doi
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|a pubmed25n1217.xml
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|a DE-627
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|c DE-627
|e rakwb
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|a eng
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| 100 |
1 |
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|a Zhao, Lingling
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Boric Acid-Functionalized Carbon Dots as a High-Performance Antibacterial Agent against Escherichia coli
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|c 2023
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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|a Date Completed 20.12.2023
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|a Date Revised 15.02.2024
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Bacterial infections and antibiotic abuse are a global threat to human health. In recent years, there has been a boom in research on antimicrobial agents with low toxicity and efficient nanomaterials. Boric acid-functionalized carbon dots (B-CDs) with negative surface charge were synthesized by the hydrothermal method. Covalent bonds were formed between the boric acid groups and the cis-diol groups of the polysaccharide in the bacterial cell wall, and numerous B-CDs were trapped on the bacterial surface. In the experiments of antibacterial activity, B-CDs presented strong bactericidal activity against Escherichia coli (E. coli) with a minimum bactericidal concentration of 12.5 μg/mL. The antibacterial mechanism suggested that B-CDs entered the cell interior by diffusion and posed significant damage to the double helix structure of E. coli DNA. Furthermore, B-CDs exhibited low toxicity. The results demonstrated that the novel antimicrobial B-CDs not only fought against E. coli infection and antibiotic misuse but also provided new ideas for safe and effective antimicrobial agents of carbon nanomaterials
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Anti-Bacterial Agents
|2 NLM
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| 650 |
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|a boric acid
|2 NLM
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| 650 |
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|a R57ZHV85D4
|2 NLM
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| 650 |
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|a Carbon
|2 NLM
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| 650 |
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|a 7440-44-0
|2 NLM
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| 650 |
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|a Anti-Infective Agents
|2 NLM
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| 700 |
1 |
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|a Ma, Yue
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Sun, Zhaomeng
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Zhang, Xiaoqing
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Liu, Mei
|e verfasserin
|4 aut
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| 773 |
0 |
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1985
|g 39(2023), 50 vom: 19. Dez., Seite 18302-18310
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnas
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| 773 |
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|g volume:39
|g year:2023
|g number:50
|g day:19
|g month:12
|g pages:18302-18310
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|u http://dx.doi.org/10.1021/acs.langmuir.3c02314
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