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|a 10.1016/j.jplph.2023.154141
|2 doi
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|e rakwb
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|a eng
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|a Tan, Jiantao
|e verfasserin
|4 aut
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|a Genome editing for plant synthetic metabolic engineering and developmental regulation
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|c 2023
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|a Text
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|a ƒaComputermedien
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|a ƒa Online-Ressource
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|a Date Completed 06.12.2023
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|a Date Revised 06.12.2023
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Copyright © 2023 Elsevier GmbH. All rights reserved.
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|a Plant metabolism and development are a reflection of the orderly expression of genetic information intertwined with the environment interactions. Genome editing is the cornerstone for scientists to modify endogenous genes or introduce exogenous functional genes and metabolic pathways, holding immense potential applications in molecular breeding and biosynthesis. Over the course of nearly a decade of development, genome editing has advanced significantly beyond the simple cutting of double-stranded DNA, now enabling precise base and fragment replacements, regulation of gene expression and translation, as well as epigenetic modifications. However, the utilization of genome editing in plant synthetic metabolic engineering and developmental regulation remains exploratory. Here, we provide an introduction and a comprehensive overview of the editing attributes associated with various CRISPR/Cas tools, along with diverse strategies for the meticulous control of plant metabolic pathways and developments. Furthermore, we discuss the limitations of current approaches and future prospects for genome editing-driven plant breeding
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|a Journal Article
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|a Review
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|a Developmental regulation
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|a Genome editing
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|a Plant breeding
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|a Synthetic metabolic engineering
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|a Shen, Mengyuan
|e verfasserin
|4 aut
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|a Chai, Nan
|e verfasserin
|4 aut
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|a Liu, Qi
|e verfasserin
|4 aut
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|a Liu, Yao-Guang
|e verfasserin
|4 aut
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|a Zhu, Qinlong
|e verfasserin
|4 aut
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|i Enthalten in
|t Journal of plant physiology
|d 1979
|g 291(2023) vom: 27. Dez., Seite 154141
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|x 1618-1328
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|g volume:291
|g year:2023
|g day:27
|g month:12
|g pages:154141
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|u http://dx.doi.org/10.1016/j.jplph.2023.154141
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