|
|
|
|
| LEADER |
01000caa a22002652 4500 |
| 001 |
NLM364641460 |
| 003 |
DE-627 |
| 005 |
20240114233817.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231226s2024 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1002/adma.202308844
|2 doi
|
| 028 |
5 |
2 |
|a pubmed24n1256.xml
|
| 035 |
|
|
|a (DE-627)NLM364641460
|
| 035 |
|
|
|a (NLM)37972577
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Ding, Lei
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a Optical Nonlinearity Enabled Super-Resolved Multiplexing Microscopy
|
| 264 |
|
1 |
|c 2024
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Revised 11.01.2024
|
| 500 |
|
|
|a published: Print-Electronic
|
| 500 |
|
|
|a Citation Status PubMed-not-MEDLINE
|
| 520 |
|
|
|a © 2023 The Authors. Advanced Materials published by Wiley-VCH GmbH.
|
| 520 |
|
|
|a Optical multiplexing for nanoscale object recognition is of great significance within the intricate domains of biology, medicine, anti-counterfeiting, and microscopic imaging. Traditionally, the multiplexing dimensions of nanoscopy are limited to emission intensity, color, lifetime, and polarization. Here, a novel dimension, optical nonlinearity, is proposed for super-resolved multiplexing microscopy. This optical nonlinearity is attributable to the energy transitions between multiple energy levels of the doped lanthanide ions in upconversion nanoparticles (UCNPs), resulting in unique optical fingerprints for UCNPs with different compositions. A vortex beam is applied to transport the optical nonlinearity onto the imaging point-spread function (PSF), creating a robust super-resolved multiplexing imaging strategy for differentiating UCNPs with distinctive optical nonlinearities. The composition information of the nanoparticles can be retrieved with variations of the corresponding PSF in the obtained image. Four channels multiplexing super-resolved imaging with a single scanning, applying emission color and nonlinearity of two orthogonal imaging dimensions with a spatial resolution higher than 150 nm (1/6.5λ), are demonstrated. This work provides a new and orthogonal dimension - optical nonlinearity - to existing multiplexing dimensions, which shows great potential in bioimaging, anti-counterfeiting, microarray assays, deep tissue multiplexing detection, and high-density data storage
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a lanthanide
|
| 650 |
|
4 |
|a multiplexing
|
| 650 |
|
4 |
|a nonlinearity
|
| 650 |
|
4 |
|a super-resolution
|
| 700 |
1 |
|
|a Chen, Chaohao
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Shan, Xuchen
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Liu, Baolei
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Wang, Dajing
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Du, Ziqing
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Zhao, Guanshu
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Su, Qian Peter
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Yang, Yang
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Halkon, Benjamin
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Tran, Toan Trong
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Liao, Jiayan
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Aharonovich, Igor
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Zhang, Min
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Cheng, Faliang
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Fu, Lan
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Xu, Xiaoxue
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Wang, Fan
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Advanced materials (Deerfield Beach, Fla.)
|d 1998
|g 36(2024), 2 vom: 10. Jan., Seite e2308844
|w (DE-627)NLM098206397
|x 1521-4095
|7 nnns
|
| 773 |
1 |
8 |
|g volume:36
|g year:2024
|g number:2
|g day:10
|g month:01
|g pages:e2308844
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1002/adma.202308844
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_350
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 36
|j 2024
|e 2
|b 10
|c 01
|h e2308844
|