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231226s2023 xx |||||o 00| ||eng c |
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|a 10.3928/23258160-20231017-01
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|a eng
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|a Chadalavada, Srila H
|e verfasserin
|4 aut
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|a Impact of Dyslipidemia Medications on the Prevalence of Diabetic Retinopathy Among a Large US Cohort
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|c 2023
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|a Text
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|a Date Completed 15.11.2023
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|a Date Revised 29.11.2023
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a BACKGROUND AND OBJECTIVE: Dyslipidemia medications such as statins and fibrates may be associated with a reduction in diabetic retinopathy (DR) progression, but real-world data is lacking. This study evaluates cholesterol-lowering medications and their association with the prevalence of DR and advanced DR complications
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|a PATIENTS AND METHODS: Data was collected using codes from the International Classification of Diseases on TriNetX, a cross-sectional database of over 79 million Americans, between June and August 2022. Prevalence and prevalence odds ratios (POR) were calculated
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|a RESULTS: Patients taking pitavastatin (OR 0.64, 95% CI 0.49, 0.84), fenofibrate (OR 0.83, CI 0.79, 0.87), or evolocumab (OR 0.80, CI 0.68, 0.95) had lower POR of proliferative DR compared to nonproliferative DR. Patients taking any cholesterol medication had a lower POR of vitreous hemorrhage. Patients taking fibrates also had lower POR of neovascular glaucoma
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|a CONCLUSION: This exploratory study highlights positive associations between DR and dyslipidemia and medications that may have fewer worsening events in DR patients. [Ophthalmic Surg Lasers Imaging Retina 2023;54:626-633.]
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|a Journal Article
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|a Cholesterol
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|a Fibric Acids
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|a Shaia, Jacqueline K
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|a Russell, Matthew W
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|a Talcott, Katherine E
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|a Singh, Rishi P
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|i Enthalten in
|t Ophthalmic surgery, lasers & imaging retina
|d 2013
|g 54(2023), 11 vom: 22. Nov., Seite 626-633
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|g volume:54
|g year:2023
|g number:11
|g day:22
|g month:11
|g pages:626-633
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