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231226s2023 xx |||||o 00| ||eng c |
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|a 10.3928/23258160-20231010-01
|2 doi
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|a pubmed24n1214.xml
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|a DE-627
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|c DE-627
|e rakwb
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|a eng
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|a Iyer, Prashanth G
|e verfasserin
|4 aut
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|a Patients With Dragged Optic Disc Vessels and Retinal Folds
|b Clinical Features, Multimodal Imaging, and Histopathology
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|c 2023
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Completed 15.11.2023
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|a Date Revised 15.11.2023
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a BACKGROUND AND OBJECTIVE: To describe the multimodal imaging and histopathological features of patients with dragged optic disc vessels (DODV)
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|a PATIENTS AND METHODS: This is a retrospective, observational analysis using multimodal imaging of eyes with DODV in patients with retinal vascular diseases including familial exudative vitreoretinopathy, inflammatory disease, and others. In addition, two additional enucleated eyes with DODV underwent histopathological analysis
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|a RESULTS: Of the 13 patients, eight were girls and five were boys. Mean age was 5 years (ranging from 4 months to 10 years old). Of the 15 eyes, 12 (80%) demonstrated temporal dragging and three (20%) had nasal dragging. Retinal vascular abnormalities were present in 11 of the fellow eyes. Multimodal imaging demonstrated features of DODV including direction of traction, outer retinal thickening, increased flow, and other features. Only two (13.3%) eyes required surgical intervention. Mean follow-up was 14 (range 3 to 30 months) months. At last follow-up all eyes remained stable. Last visual acuity ranged from 20/100 to counting fingers. As well, two enucleated globes of adults with retinopathy of prematurity underwent histopathologic evaluation, showing optic nerve fibers that extended from the optic nerve into the DODV
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|a CONCLUSIONS: DODV is a sign of various late-stage retinal vascular diseases, associated with poor visual function. Multimodal imaging and histopathology can assist in understanding the disease pathology. [Ophthalmic Surg Lasers Imaging Retina 2023;54:634-642.]
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|a Observational Study
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|a Journal Article
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|a Ashkenazy, Noy
|e verfasserin
|4 aut
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|a Carletti, Piero
|e verfasserin
|4 aut
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|a Hudson, Julia L
|e verfasserin
|4 aut
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|a Patel, Nimesh A
|e verfasserin
|4 aut
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|a Sengillo, Jesse D
|e verfasserin
|4 aut
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|a Kunkler, Anne L
|e verfasserin
|4 aut
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|a Lazzarini, Thomas A
|e verfasserin
|4 aut
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|a Khzam, Rayan Abou
|e verfasserin
|4 aut
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|a Tang, Vincent
|e verfasserin
|4 aut
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|a Negron, Catherin I
|e verfasserin
|4 aut
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|a Dubovy, Sander
|e verfasserin
|4 aut
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|a Flynn, Harry W
|c Jr
|e verfasserin
|4 aut
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|a Berrocal, Audina M
|e verfasserin
|4 aut
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|i Enthalten in
|t Ophthalmic surgery, lasers & imaging retina
|d 2013
|g 54(2023), 11 vom: 13. Nov., Seite 634-642
|w (DE-627)NLM224956647
|x 2325-8179
|7 nnns
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1 |
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|g volume:54
|g year:2023
|g number:11
|g day:13
|g month:11
|g pages:634-642
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|u http://dx.doi.org/10.3928/23258160-20231010-01
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