Evaluation of resistance risk in soil due to antibiotics during application of penicillin V fermentation residue

The soil application of hydrothermally treated penicillin V fermentation residue (PFR) is attractive but challenged, due to the concern of the resistance risk in soil related to residual antibiotics. In this study, a lab-scale incubation experiment was conducted to investigate the influence of penic...

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Veröffentlicht in:Environmental technology. - 1993. - 45(2024), 24 vom: 08. Sept., Seite 5173-5181
1. Verfasser: Gong, Picheng (VerfasserIn)
Weitere Verfasser: Liu, Huiling, Yu, Tingting, Jiang, Cuishuang, Gou, Enfang, Guan, Jingze, Chen, Huayuan, Kang, Haoze
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2024
Zugriff auf das übergeordnete Werk:Environmental technology
Schlagworte:Journal Article Antibiotic resistance gene fermentation residue hydrothermal treatment penicillin V soil application Anti-Bacterial Agents Penicillin V Z61I075U2W Soil Pollutants Soil
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520 |a The soil application of hydrothermally treated penicillin V fermentation residue (PFR) is attractive but challenged, due to the concern of the resistance risk in soil related to residual antibiotics. In this study, a lab-scale incubation experiment was conducted to investigate the influence of penicillin V on antibiotic resistance genes (ARGs) in PFR-amended soil via qPCR. The introduced penicillin V in soil could not be persistent, and its degradation occurred mainly within 2 days. The higher number of soil ARGs was detected under 108 mg/kg of penicillin V than lower contents (≤54 mg/kg). Additionally, the relative abundance of ARGs was higher in soil spiked with penicillin V than that in blank soil, and the great increase in the relative abundance of soil ARGs occurred earlier under 108 mg/kg of penicillin V than lower contents. The horizontal gene transfer might contribute to the shift of ARGs in PFR-amended soil. The results indicated that the residual penicillin V could cause the proliferation of soil ARGs and should be completely removed by hydrothermal treatment before soil application. The results of this study provide a comprehensive understanding of the resistance risk posed by penicillin V during the application of hydrothermally pretreated PFR 
650 4 |a Journal Article 
650 4 |a Antibiotic resistance gene 
650 4 |a fermentation residue 
650 4 |a hydrothermal treatment 
650 4 |a penicillin V 
650 4 |a soil application 
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650 7 |a Penicillin V  |2 NLM 
650 7 |a Z61I075U2W  |2 NLM 
650 7 |a Soil Pollutants  |2 NLM 
650 7 |a Soil  |2 NLM 
700 1 |a Liu, Huiling  |e verfasserin  |4 aut 
700 1 |a Yu, Tingting  |e verfasserin  |4 aut 
700 1 |a Jiang, Cuishuang  |e verfasserin  |4 aut 
700 1 |a Gou, Enfang  |e verfasserin  |4 aut 
700 1 |a Guan, Jingze  |e verfasserin  |4 aut 
700 1 |a Chen, Huayuan  |e verfasserin  |4 aut 
700 1 |a Kang, Haoze  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Environmental technology  |d 1993  |g 45(2024), 24 vom: 08. Sept., Seite 5173-5181  |w (DE-627)NLM098202545  |x 1479-487X  |7 nnns 
773 1 8 |g volume:45  |g year:2024  |g number:24  |g day:08  |g month:09  |g pages:5173-5181 
856 4 0 |u http://dx.doi.org/10.1080/09593330.2023.2283807  |3 Volltext 
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