Electrostatic-Mediated Binding of DNA to Lysozymes : Evaluation of Aptamer-Based Assays for Highly Positively Charged Targets

Lysozymes are a highly popular protein target for the development of aptamer-based biosensors. Because a lysozyme is a polycation and DNA is a polyanion, it is essential to separate the contribution of nonspecific electrostatic interactions from specific aptamer binding. In this study, various facto...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 39(2023), 41 vom: 17. Okt., Seite 14774-14781
1. Verfasser: Shi, Lu (VerfasserIn)
Weitere Verfasser: Jin, Yan, Liu, Juewen
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2023
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Muramidase EC 3.2.1.17 Gold 7440-57-5 Aptamers, Nucleotide DNA 9007-49-2