Interface-Stabilized Fiber Sensor for Real-Time Monitoring of Amniotic Fluid During Pregnancy

Interface-Stabilized Fiber Sensor for Real-Time Monitoring of Amniotic Fluid During Pregnancy

© 2023 Wiley-VCH GmbH.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 36(2024), 6 vom: 20. Feb., Seite e2307726
1. Verfasser: Li, Qianming (VerfasserIn)
Weitere Verfasser: Li, Dan, Lu, Jiang, Zou, Kuangyi, Wang, Lie, Jiao, Yiding, Wang, Maosen, Gao, Rui, Song, Jie, Li, Yiran, Li, Fangyan, Ji, Jianjian, Wang, Jiacheng, Li, Luhe, Ye, Tingting, He, Er, Chen, Hao, Wang, Yuanzhen, Ren, Junye, Bai, Chenyu, Yang, Shuo, Zhang, Ye
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2024
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article early warning fiber sensor real-time monitoring restorative gel tissue-device interface
Beschreibung
Zusammenfassung:© 2023 Wiley-VCH GmbH.
Diseases in pregnancy endanger millions of fetuses worldwide every year. The onset of these diseases can be early warned by the dynamic abnormalities of biochemicals in amniotic fluid, thus requiring real-time monitoring. However, when continuously penetrated by detection devices, the amnion is prone to loss of robustness and rupture, which is difficult to regenerate. Here, an interface-stabilized fiber sensor is presented for real-time monitoring of biochemical dynamics in amniotic fluid during pregnancy. The sensor is seamlessly integrated into the amnion through tissue adhesion, amniotic regeneration, and uniform stress distribution, posing no risk to the amniotic fluid environment. The sensor demonstrates a response performance of less than 0.3% fluctuation under complex dynamic conditions and an accuracy of more than 98% from the second to the third trimester. By applying it to early warning of diseases such as intrauterine hypoxia, intrauterine infection, and fetal growth restriction, fetal survival increases to 95% with timely intervention
Beschreibung:Date Completed 14.02.2024
Date Revised 14.02.2024
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.202307726