Soft, Long-Lived, Bioresorbable Electronic Surgical Mesh with Wireless Pressure Monitor and On-Demand Drug Delivery

Soft, Long-Lived, Bioresorbable Electronic Surgical Mesh with Wireless Pressure Monitor and On-Demand Drug Delivery

© 2023 Wiley-VCH GmbH.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 36(2024), 11 vom: 01. März, Seite e2307391
1. Verfasser: Kaveti, Rajaram (VerfasserIn)
Weitere Verfasser: Lee, Joong Hoon, Youn, Joong Kee, Jang, Tae-Min, Han, Won Bae, Yang, Seung Min, Shin, Jeong-Woong, Ko, Gwan-Jin, Kim, Dong-Je, Han, Sungkeun, Kang, Heeseok, Bandodkar, Amay J, Kim, Hyun-Young, Hwang, Suk-Won
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2024
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article biodegradable elastomer hernia repair surgical mesh transient electronics wireless pressure sensor
Beschreibung
Zusammenfassung:© 2023 Wiley-VCH GmbH.
Current research in the area of surgical mesh implants is somewhat limited to traditional designs and synthesis of various mesh materials, whereas meshes with multiple functions may be an effective approach to address long-standing challenges including postoperative complications. Herein, a bioresorbable electronic surgical mesh is presented that offers high mechanical strength over extended timeframes, wireless post-operative pressure monitoring, and on-demand drug delivery for the restoration of tissue structure and function. The study of materials and mesh layouts provides a wide range of tunability of mechanical and biochemical properties. Dissolvable dielectric composite with porous structure in a pyramidal shape enhances sensitivity of a wireless capacitive pressure sensor, and resistive microheaters integrated with inductive coils provide thermo-responsive drug delivery system for an antibacterial agent. In vivo evaluations demonstrate reliable, long-lived operation, and effective treatment for abdominal hernia defects, by clear evidence of suppressed complications such as adhesion formation and infections
Beschreibung:Date Completed 15.03.2024
Date Revised 15.03.2024
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.202307391