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|a 10.3928/23258160-20230825-01
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|a eng
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1 |
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|a O'Riordan, Matthew M
|e verfasserin
|4 aut
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|a Evaluation of Inflammation in the Peripheral Multiple Sclerosis Retina Using Ultra-Widefield Optical Coherence Tomography
|b A Pilot Study
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|c 2023
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|a Text
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|a ƒaComputermedien
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|a Date Completed 23.10.2023
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|a Date Revised 29.10.2023
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a BACKGROUND AND OBJECTIVE: Reports of fundus fluorescein angiography (FFA) in active multiple sclerosis (MS) have shown peripheral perivenous sheathing. We sought to assess the feasibility of ultra-widefield (UWF) FFA and optical coherence tomography (OCT) in assessing the peripheral retina in MS
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|a MATERIALS AND METHODS: Participants with MS and healthy controls underwent bilateral UWF fundus photography and FFA. Swept-source OCTs were captured centrally, peripherally, and to delineate any abnormalities visualized
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|a RESULTS: We recruited five people with relapsing remitting MS, with a mean age of 36.9 (± 9.9), mean disease duration of 11 years (± 6.3), and a median expanded disability status score of 0.75 (0 to 2.5). In all MS participants, the disease was not active clinically or radiologically. Using UWF-FFA and OCT, we did not detect clear evidence of peripheral retinal abnormalities, which is consistent with the participants having inactive MS
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|a CONCLUSION: A pilot study using UWF-FFA and peripheral OCT to examine the retina in MS suggests that it may be useful to perform a larger prospective longitudinal study to establish its potential as a monitor of disease activity. [Ophthalmic Surg Lasers Imaging Retina 2023;54:586-588.]
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|a Journal Article
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|a Cahill, Mark T
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|a Campbell, Matthew
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| 700 |
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|a Kearney, Hugh
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|t Ophthalmic surgery, lasers & imaging retina
|d 2013
|g 54(2023), 10 vom: 11. Okt., Seite 586-588
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|g volume:54
|g year:2023
|g number:10
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|g month:10
|g pages:586-588
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|u http://dx.doi.org/10.3928/23258160-20230825-01
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