Cancer-Associated Gangliosides as a Therapeutic Target for Host Defense Peptide Mimics

Aberrant levels of glycolipids expressed on cellular surfaces are characteristic of different types of cancers. The oligomer of acylated lysine (OAK) mimicking antimicrobial peptides displays in vitro activity against human and murine melanoma cell lines with upregulated GD3 and GM3 gangliosides. He...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Langmuir : the ACS journal of surfaces and colloids. - 1999. - 39(2023), 36 vom: 12. Sept., Seite 12541-12549
1. Verfasser:	Martynowycz, Michael W (VerfasserIn)
Weitere Verfasser:	Andreev, Konstantin, Mor, Amram, Gidalevitz, David
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2023
Zugriff auf das übergeordnete Werk:	Langmuir : the ACS journal of surfaces and colloids
Schlagworte:	Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S. Research Support, Non-U.S. Gov't Gangliosides Antimicrobial Cationic Peptides Glycolipids