Diffraction anisotropy and paired refinement : crystal structure of H33, a protein binder to interleukin 10
© Petr Kolenko et al. 2023.
| Veröffentlicht in: | Journal of applied crystallography. - 1998. - 56(2023), Pt 4 vom: 01. Aug., Seite 1261-1266 |
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| 1. Verfasser: | |
| Weitere Verfasser: | , , , |
| Format: | Online-Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
2023
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| Zugriff auf das übergeordnete Werk: | Journal of applied crystallography |
| Schlagworte: | Journal Article anisotropy binder H33 paired refinement |
| Zusammenfassung: | © Petr Kolenko et al. 2023. Binder H33 is a small protein binder engineered by ribosome display to bind human interleukin 10. Crystals of binder H33 display severe diffraction anisotropy. A set of data files with correction for diffraction anisotropy based on different local signal-to-noise ratios was prepared. Paired refinement was used to find the optimal anisotropic high-resolution diffraction limit of the data: 3.13-2.47 Å. The structure of binder H33 belongs to the 2% of crystal structures with the highest solvent content in the Protein Data Bank |
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| Beschreibung: | Date Revised 10.08.2023 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
| ISSN: | 0021-8898 |
| DOI: | 10.1107/S160057672300479X |