Bactericidal role of epidermal mucus of freshwater fish treated with Aeromonas hydrophila

© 2023 John Wiley & Sons Ltd.

Bibliographische Detailangaben
Veröffentlicht in:Journal of fish diseases. - 1998. - 46(2023), 11 vom: 12. Nov., Seite 1225-1237
1. Verfasser: Ali, Shandana (VerfasserIn)
Weitere Verfasser: Shah, Syed Ata Ur Rahman, Rauf, Muhammad, Hassan, Maizom, Ullah, Waheed, Dawar, Farman Ullah
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2023
Zugriff auf das übergeordnete Werk:Journal of fish diseases
Schlagworte:Journal Article Cyprinid SDS-PAGE bactericidal activity minimum inhibitory concentration pathogenic bacteria Fosfomycin 2N81MY12TE Anti-Bacterial Agents
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520 |a This study explored the bactericidal role of the epidermal mucus (EM) of five freshwater Cyprinid fish species namely Ctenopharyngodon idella, Labeo rohita, Catla catla, Hypophthalmichthys molitrix, and Cirrhinus mrigala after treatment with Aeromonas hydrophila. Extracts of EM (crude and acidic) of each species showed bactericidal activity against various Gram -ve (Pseudomonas aeruginosa, Escherichia coli, Aeromonas hydrophila, Edwardsiella tarda, Salmonella enterica, Klebsiella pneumonia, Serratia marcescens, and Enterobacter cloacae) and Gram +ve (Bacillus wiedmannii and Staphylococcus aureus) bacteria compared with standard antibiotics (Fosfomycin). The zone of inhibition (ZOI) was measured in millimetres against antibiotics (Fosfomycin). Variations in bactericidal activity of EM were observed against bacteria from the same and different fish species. The acidic extract was more effective than the crude extract and showed significantly higher ZOI values against various bacteria and Fosfomycin antibiotics. This result shows that fish EM may perform an important role in fish defence against bacteria. Therefore, this study may hint towards the substitution of synthetic antibiotics with fish EM that may be used as a novel 'bactericidal' in aquaculture as well as in humans against bacterial infections 
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650 4 |a bactericidal activity 
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650 4 |a pathogenic bacteria 
650 7 |a Fosfomycin  |2 NLM 
650 7 |a 2N81MY12TE  |2 NLM 
650 7 |a Anti-Bacterial Agents  |2 NLM 
700 1 |a Shah, Syed Ata Ur Rahman  |e verfasserin  |4 aut 
700 1 |a Rauf, Muhammad  |e verfasserin  |4 aut 
700 1 |a Hassan, Maizom  |e verfasserin  |4 aut 
700 1 |a Ullah, Waheed  |e verfasserin  |4 aut 
700 1 |a Dawar, Farman Ullah  |e verfasserin  |4 aut 
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773 1 8 |g volume:46  |g year:2023  |g number:11  |g day:12  |g month:11  |g pages:1225-1237 
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