Sensitive and specific quantification of antisense oligonucleotides using probe alteration-linked self-assembly reaction technology
Quantitative bioanalysis is essential when establishing pharmacokinetic properties during the drug development process. To overcome challenges of sensitivity, specificity and process complexity associated with the conventional analysis of antisense oligonucleotides (ASOs), a new approach to nonenzym...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | BioTechniques. - 1991. - 75(2023), 1 vom: 11. Juli, Seite 353-362
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| 1. Verfasser: |
Osawa, Masako
(VerfasserIn) |
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| Weitere Verfasser: |
Akiya, Takurou,
Ogawa, Funa,
Suzuki, Takao,
Yamagami, Masaki,
Umemoto, Tadashi,
Ideno, Akira |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2023
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| Zugriff auf das übergeordnete Werk: | BioTechniques
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| Schlagworte: | Journal Article
PALSAR technology
antisense oligonucleotide
bioanalysis
ligand-binding assay
nonenzymatic hybridization assay
sensitivity
specificity
Oligonucleotides, Antisense |
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