Intrinsic Brain Functional Activity Abnormalities in Episodic Tension-Type Headache

Copyright © 2023 Xiu Yang et al.

Détails bibliographiques
Publié dans:Neural plasticity. - 1998. - 2023(2023) vom: 29., Seite 6560298
Auteur principal: Yang, Xiu (Auteur)
Autres auteurs: Guo, DianXuan, Huang, Wei, Chen, Bing
Format: Article en ligne
Langue:English
Publié: 2023
Accès à la collection:Neural plasticity
Sujets:Journal Article
Description
Résumé:Copyright © 2023 Xiu Yang et al.
Objective: The neurobiological basis of episodic tension-type headache (ETTH) remains largely unclear. The aim of the present study was to explore intrinsic brain functional activity alterations in ETTH
Methods: Resting-state functional magnetic resonance imaging (rs-fMRI) data were collected from 32 patients with ETTH and 32 age- and gender-matched healthy controls (HCs). Differences in intrinsic brain functional activity between patients with ETTH and HCs were analyzed utilizing the fractional amplitude of low-frequency fluctuation (fALFF) approach. Correlation analyses were performed to examine the relationship between fALFF alterations and clinical characteristics
Results: Compared to HCs, patients with ETTH exhibited increased fALFF in the right posterior insula and anterior insula and decreased fALFF in the posterior cingulate cortex. Moreover, the fALFF in the right anterior insula was negatively correlated with attack frequency in ETTH
Conclusions: This study highlights alterations in the intrinsic brain functional activity in the insula and posterior cingulate cortex in ETTH that can help us understand its neurobiological underpinnings
Description:Date Completed 05.06.2023
Date Revised 05.06.2023
published: Electronic-eCollection
Citation Status MEDLINE
ISSN:1687-5443
DOI:10.1155/2023/6560298