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231226s2023 xx |||||o 00| ||eng c |
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|a 10.1093/jxb/erad204
|2 doi
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|a pubmed24n1191.xml
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|a (DE-627)NLM357515102
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|a (NLM)37249342
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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| 100 |
1 |
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|a Hoffmann, Gesa
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Cauliflower mosaic virus disease spectrum uncovers novel susceptibility factor NCED9 in Arabidopsis thaliana
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|c 2023
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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| 338 |
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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| 500 |
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|a Date Completed 21.08.2023
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|a Date Revised 21.08.2023
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|a published: Print
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|a Citation Status MEDLINE
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|a © The Author(s) 2023. Published by Oxford University Press on behalf of the Society for Experimental Biology.
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|a Viruses are intimately linked with their hosts and especially dependent on gene-for-gene interactions to establish successful infections. On the host side, defence mechanisms such as tolerance and resistance can occur within the same species, leading to differing virus accumulation in relation to symptomology and plant fitness. The identification of novel resistance genes against viruses and susceptibility factors is an important part of understanding viral patho-genesis and securing food production. The model plant Arabidopsis thaliana displays a wide symptom spectrum in response to RNA virus infections, and unbiased genome-wide association studies have proven a powerful tool to identify novel disease-genes. In this study we infected natural accessions of A. thaliana with the pararetrovirus cauliflower mosaic virus (CaMV) to study the phenotypic variations between accessions and their correlation with virus accumulation. Through genome-wide association mapping of viral accumulation differences, we identified several susceptibility factors for CaMV, the strongest of which was the abscisic acid synthesis gene NCED9. Further experiments confirmed the importance of abscisic acid homeostasis and its disruption for CaMV disease
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Abscisic acid
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| 650 |
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4 |
|a Arabidopsis
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| 650 |
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|a cauliflower mosaic virus
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| 650 |
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|a genome-wide association studies
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|a virus disease
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|a virus tolerance
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| 650 |
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|a Abscisic Acid
|2 NLM
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|a 72S9A8J5GW
|2 NLM
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| 650 |
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|a 9-cis-epoxy-carotenoid dioxygenase
|2 NLM
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| 650 |
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|a EC 1.13.11.51
|2 NLM
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| 700 |
1 |
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|a Shukla, Aayushi
|e verfasserin
|4 aut
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| 700 |
1 |
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|a López-González, Silvia
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Hafrén, Anders
|e verfasserin
|4 aut
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| 773 |
0 |
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|i Enthalten in
|t Journal of experimental botany
|d 1985
|g 74(2023), 15 vom: 17. Aug., Seite 4751-4764
|w (DE-627)NLM098182706
|x 1460-2431
|7 nnns
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| 773 |
1 |
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|g volume:74
|g year:2023
|g number:15
|g day:17
|g month:08
|g pages:4751-4764
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|u http://dx.doi.org/10.1093/jxb/erad204
|3 Volltext
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