Hypoxia-responsive Immunostimulatory Nanomedicines Synergize with Checkpoint Blockade Immunotherapy for Potentiating Cancer Immunotherapy

Inducing cell death while simultaneously enhancing antitumor immune responses is a promising therapeutic approach for multiple cancers. Celastrol (Cel) and 7-ethyl-10-hydroxycamptothecin (SN38) have contrasting physicochemical properties, but strong synergy in immunogenic cell death induction and an...

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Veröffentlicht in:Chemical engineering journal (Lausanne, Switzerland : 1996). - 1999. - 451(2023), Pt 2 vom: 06. Jan.
1. Verfasser: Chen, Weiguo (VerfasserIn)
Weitere Verfasser: Sheng, Ping, Chen, Yujiang, Liang, Yi, Wu, Sixin, Jia, Liying, He, Xin, Zhang, Chun-Feng, Wang, Chong-Zhi, Yuan, Chun-Su
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2023
Zugriff auf das übergeordnete Werk:Chemical engineering journal (Lausanne, Switzerland : 1996)
Schlagworte:Journal Article Cancer immunotherapy Covalent organic frameworks Immunogenic cell death Immunogenic nanomedicine