|
|
|
|
| LEADER |
01000naa a22002652 4500 |
| 001 |
NLM355008556 |
| 003 |
DE-627 |
| 005 |
20231226063437.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231226s2023 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1002/adma.202300191
|2 doi
|
| 028 |
5 |
2 |
|a pubmed24n1183.xml
|
| 035 |
|
|
|a (DE-627)NLM355008556
|
| 035 |
|
|
|a (NLM)36995927
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Mayorga-Martinez, Carmen C
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a Multimodal-Driven Magnetic Microrobots with Enhanced Bactericidal Activity for Biofilm Eradication and Removal from Titanium Mesh
|
| 264 |
|
1 |
|c 2023
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 09.06.2023
|
| 500 |
|
|
|a Date Revised 09.06.2023
|
| 500 |
|
|
|a published: Print-Electronic
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a © 2023 The Authors. Advanced Materials published by Wiley-VCH GmbH.
|
| 520 |
|
|
|a Modern micro/nanorobots can perform multiple tasks for biomedical and environmental applications. Particularly, magnetic microrobots can be completely controlled by a rotating magnetic field and their motion powered and controlled without the use of toxic fuels, which makes them most promising for biomedical application. Moreover, they are able to form swarms, allowing them to perform specific tasks at a larger scale than a single microrobot. In this work, they developed magnetic microrobots composed of halloysite nanotubes as backbone and iron oxide (Fe3 O4 ) nanoparticles as magnetic material allowing magnetic propulsion and covered these with polyethylenimine to load ampicillin and prevent the microrobots from disassembling. These microrobots exhibit multimodal motion as single robots as well as in swarms. In addition, they can transform from tumbling to spinning motion and vice-versa, and when in swarm mode they can change their motion from vortex to ribbon and back again. Finally, the vortex motion mode is used to penetrate and disrupt the extracellular matrix of Staphylococcus aureus biofilm colonized on titanium mesh used for bone restoration, which improves the effect of the antibiotic's activity. Such magnetic microrobots for biofilm removal from medical implants could reduce implant rejection and improve patients' well-being
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a collective behavior
|
| 650 |
|
4 |
|a ribbons
|
| 650 |
|
4 |
|a swarms
|
| 650 |
|
4 |
|a vortices
|
| 650 |
|
7 |
|a Titanium
|2 NLM
|
| 650 |
|
7 |
|a D1JT611TNE
|2 NLM
|
| 700 |
1 |
|
|a Zelenka, Jaroslav
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Klima, Karel
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Kubanova, Michaela
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Ruml, Tomas
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Pumera, Martin
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Advanced materials (Deerfield Beach, Fla.)
|d 1998
|g 35(2023), 23 vom: 01. Juni, Seite e2300191
|w (DE-627)NLM098206397
|x 1521-4095
|7 nnns
|
| 773 |
1 |
8 |
|g volume:35
|g year:2023
|g number:23
|g day:01
|g month:06
|g pages:e2300191
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1002/adma.202300191
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_350
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 35
|j 2023
|e 23
|b 01
|c 06
|h e2300191
|