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20231226062826.0 |
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231226s2023 xx |||||o 00| ||eng c |
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|a 10.1016/j.clim.2023.109302
|2 doi
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|a pubmed24n1182.xml
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|a (NLM)36967025
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|a (PII)S1521-6616(23)00081-5
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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| 100 |
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|a Giardino, Giuliana
|e verfasserin
|4 aut
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|a Immune tolerance breakdown in inborn errors of immunity
|b Paving the way to novel therapeutic approaches
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|c 2023
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|2 rdamedia
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|a ƒa Online-Ressource
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|a Date Completed 25.05.2023
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|a Date Revised 25.05.2023
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Copyright © 2023. Published by Elsevier Inc.
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|a Up to 25% of the patients with inborn errors of immunity (IEI) also exhibit immunodysregulatory features. The association of immune dysregulation and immunodeficiency may be explained by different mechanisms. The understanding of mechanisms underlying immune dysregulation in IEI has paved the way for the development of targeted treatments. In this review article, we will summarize the mechanisms of immune tolerance breakdown and the targeted therapeutic approaches to immune dysregulation in IEI
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|a Journal Article
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|a Review
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|a Autoimmunity
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|a Immune tolerance
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|a Immunodysregulation
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|a Inborn errors of immunity
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|a T Reg
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1 |
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|a Romano, Roberta
|e verfasserin
|4 aut
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|a Lougaris, Vassilios
|e verfasserin
|4 aut
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| 700 |
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|a Castagnoli, Riccardo
|e verfasserin
|4 aut
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|a Cillo, Francesca
|e verfasserin
|4 aut
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|a Leonardi, Lucia
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|4 aut
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|a La Torre, Francesco
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|a Soresina, Annarosa
|e verfasserin
|4 aut
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|a Federici, Silvia
|e verfasserin
|4 aut
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|a Cancrini, Caterina
|e verfasserin
|4 aut
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|a Pacillo, Lucia
|e verfasserin
|4 aut
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|a Toriello, Elisabetta
|e verfasserin
|4 aut
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|a Cinicola, Bianca Laura
|e verfasserin
|4 aut
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|a Corrente, Stefania
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|a Volpi, Stefano
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|4 aut
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|a Marseglia, Gian Luigi
|e verfasserin
|4 aut
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|a Pignata, Claudio
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|a Cardinale, Fabio
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|4 aut
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|a Immunology Task Force of the Italian Society of Pediatric Allergy and Immunology (SIAIP)
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Clinical immunology (Orlando, Fla.)
|d 1999
|g 251(2023) vom: 24. Juni, Seite 109302
|w (DE-627)NLM098196855
|x 1521-7035
|7 nnns
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| 773 |
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|g volume:251
|g year:2023
|g day:24
|g month:06
|g pages:109302
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|u http://dx.doi.org/10.1016/j.clim.2023.109302
|3 Volltext
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