|
|
|
|
| LEADER |
01000caa a22002652 4500 |
| 001 |
NLM354648799 |
| 003 |
DE-627 |
| 005 |
20231227131156.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231226s2023 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1093/jxb/erad108
|2 doi
|
| 028 |
5 |
2 |
|a pubmed24n1225.xml
|
| 035 |
|
|
|a (DE-627)NLM354648799
|
| 035 |
|
|
|a (NLM)36959729
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Fabian, Matthew L
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a Steroidal glycoalkaloids contribute to anthracnose resistance in Solanum lycopersicum
|
| 264 |
|
1 |
|c 2023
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 29.06.2023
|
| 500 |
|
|
|a Date Revised 09.12.2023
|
| 500 |
|
|
|a published: Print
|
| 500 |
|
|
|a ErratumIn: J Exp Bot. 2023 Dec 09;:. - PMID 38070131
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a © The Author(s) 2023. Published by Oxford University Press on behalf of the Society for Experimental Biology. All rights reserved. For permissions, please email: journals.permissionsoup.com.
|
| 520 |
|
|
|a Anthracnose is a widespread plant disease caused by various species of the fungal pathogen Colletotrichum. In solanaceous plants such as tomato (Solanum lycopersicum), Colletotrichum infections exhibit a quiescent, asymptomatic state in developing fruit, followed by a transition to necrotrophic infections in ripe fruit. Through analysis of fruit tissue extracts of 95L368, a tomato breeding line that yields fruit with enhanced anthracnose resistance, we identified a role for steroidal glycoalkaloids (SGAs) in anthracnose resistance. The SGA α-tomatine and several of its derivatives accumulated at higher levels, in comparison with fruit of the susceptible tomato cultivar US28, and 95L368 fruit extracts displayed fungistatic activity against Colletotrichum. Correspondingly, ripe and unripe 95L368 fruit displayed enhanced expression of glycoalkaloid metabolic enzyme (GAME) genes, which encode key enzymes in SGA biosynthesis. Metabolomics analysis incorporating recombinant inbred lines generated from 95L368 and US28 yielded strong positive correlations between anthracnose resistance and accumulation of α-tomatine and several derivatives. Lastly, transient silencing of expression of the GAME genes GAME31 and GAME5 in anthracnose-susceptible tomato fruit yielded enhancements to anthracnose resistance. Together, our data support a role for SGAs in anthracnose defense in tomato, with a distinct SGA metabolomic profile conferring resistance to virulent Colletotrichum infections in ripe fruit
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a Research Support, U.S. Gov't, Non-P.H.S.
|
| 650 |
|
4 |
|a Colletotrichum
|
| 650 |
|
4 |
|a Solanum lycopersicum
|
| 650 |
|
4 |
|a Anthracnose
|
| 650 |
|
4 |
|a GAME2
|
| 650 |
|
4 |
|a GAME31
|
| 650 |
|
4 |
|a GAME4
|
| 650 |
|
4 |
|a GAME5
|
| 650 |
|
4 |
|a metabolomics
|
| 650 |
|
4 |
|a steroidal glycoalkaloids
|
| 650 |
|
4 |
|a tomato
|
| 700 |
1 |
|
|a Zhang, Chong
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Sun, Jianghao
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Price, Neil P
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Chen, Pei
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Clarke, Christopher R
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Jones, Richard W
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Stommel, John R
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Journal of experimental botany
|d 1985
|g 74(2023), 12 vom: 27. Juni, Seite 3700-3713
|w (DE-627)NLM098182706
|x 1460-2431
|7 nnns
|
| 773 |
1 |
8 |
|g volume:74
|g year:2023
|g number:12
|g day:27
|g month:06
|g pages:3700-3713
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1093/jxb/erad108
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_350
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 74
|j 2023
|e 12
|b 27
|c 06
|h 3700-3713
|