Bioreactor Expansion Reconfigures Metabolism and Extracellular Vesicle Biogenesis of Human Adipose-derived Stem Cells In Vitro
Human mesenchymal stem cells (hMSCs), including human adipose tissue-derived stem cells (hASCs), as well as the secreted extracellular vesicles (EVs), are promising therapeutics in treating inflammatory and neural degenerative diseases. However, prolonged expansion can lead to cellular senescence ch...
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Détails bibliographiques
| Publié dans: | Biochemical engineering journal. - 1998. - 188(2022) vom: 15. Dez.
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| Auteur principal: |
Jeske, Richard
(Auteur) |
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| Autres auteurs: |
Chen, Xingchi,
Ma, Shaoyang,
Zeng, Eric Z,
Driscoll, Tristan,
Li, Yan |
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| Format: | Article en ligne
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| Langue: | English |
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| Publié: |
2022
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| Accès à la collection: | Biochemical engineering journal
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| Sujets: | Journal Article
extracellular vesicles
human mesenchymal stem cells
metabolism
senescence
spinner bioreactor |
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