Bioreactor Expansion Reconfigures Metabolism and Extracellular Vesicle Biogenesis of Human Adipose-derived Stem Cells In Vitro

Human mesenchymal stem cells (hMSCs), including human adipose tissue-derived stem cells (hASCs), as well as the secreted extracellular vesicles (EVs), are promising therapeutics in treating inflammatory and neural degenerative diseases. However, prolonged expansion can lead to cellular senescence ch...

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Bibliographische Detailangaben

Veröffentlicht in:	Biochemical engineering journal. - 1998. - 188(2022) vom: 15. Dez.
1. Verfasser:	Jeske, Richard (VerfasserIn)
Weitere Verfasser:	Chen, Xingchi, Ma, Shaoyang, Zeng, Eric Z, Driscoll, Tristan, Li, Yan
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2022
Zugriff auf das übergeordnete Werk:	Biochemical engineering journal
Schlagworte:	Journal Article extracellular vesicles human mesenchymal stem cells metabolism senescence spinner bioreactor