Diterpenes of Coffea seeds show antifungal and anti-insect activities and are transferred from the endosperm to the seedling after germination

Copyright © 2022 Elsevier Masson SAS. All rights reserved.

Bibliographische Detailangaben
Veröffentlicht in:Plant physiology and biochemistry : PPB. - 1991. - 194(2023) vom: 01. Jan., Seite 627-637
1. Verfasser: Antoine, Gaëlle (VerfasserIn)
Weitere Verfasser: Vaissayre, Virginie, Meile, Jean-Christophe, Payet, Jim, Conéjéro, Geneviève, Costet, Laurent, Fock-Bastide, Isabelle, Joët, Thierry, Dussert, Stéphane
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2023
Zugriff auf das übergeordnete Werk:Plant physiology and biochemistry : PPB
Schlagworte:Journal Article Biological activity Cafestol Coffea arabica Coffea mauritiana Ent-Kaurane diterpenoids GC HPLC Kahweol Microscopy mehr... Rubiaceae Coffee cafestol palmitate 81760-46-5 cafestol AC465T6Q6W Antifungal Agents Diterpenes Fatty Acids
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245 1 0 |a Diterpenes of Coffea seeds show antifungal and anti-insect activities and are transferred from the endosperm to the seedling after germination 
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520 |a Species of the genus Coffea accumulate diterpenes of the ent-kaurane family in the endosperm of their seeds, of which cafestol and kahweol are the most abundant. The diterpenes are mainly stored in esterified form with fatty acids, mostly palmitate. In contrast to the numerous studies on their effects on human health and therapeutic applications, nothing was previously known about their biological and ecological role in planta. The antifungal and anti-insect activities of cafestol and cafestol palmitate were thus investigated in this study. Cafestol significantly affected the mycelial growth of five of the six phytopathogenic fungi tested. It also greatly reduced the percentage of pupation of larvae and the pupae and adult masses of one of the two fruit flies tested. By contrast, cafestol palmitate had no significant effect against any of the fungi and insects studied. Using confocal imaging and oil body isolation and analysis, we showed that diterpenes are localized in endosperm oil bodies, suggesting that esterification with fatty acids enables the accumulation of large amounts of diterpenes in a non-toxic form. Diterpene measurements in all organs of seedlings recovered from whole seed germination or embryos isolated from the endosperm showed that diterpenes are transferred from the endosperm to the cotyledons during seedling growth and then distributed to all organs, including the hypocotyl and the root. Collectively, our findings show that coffee diterpenes are broad-spectrum defence compounds that protect not only the seed on the mother plant and in the soil, but also the seedling after germination 
650 4 |a Journal Article 
650 4 |a Biological activity 
650 4 |a Cafestol 
650 4 |a Coffea arabica 
650 4 |a Coffea mauritiana 
650 4 |a Ent-Kaurane diterpenoids 
650 4 |a GC 
650 4 |a HPLC 
650 4 |a Kahweol 
650 4 |a Microscopy 
650 4 |a Rubiaceae 
650 7 |a Coffee  |2 NLM 
650 7 |a cafestol palmitate  |2 NLM 
650 7 |a 81760-46-5  |2 NLM 
650 7 |a cafestol  |2 NLM 
650 7 |a AC465T6Q6W  |2 NLM 
650 7 |a Antifungal Agents  |2 NLM 
650 7 |a Diterpenes  |2 NLM 
650 7 |a Fatty Acids  |2 NLM 
700 1 |a Vaissayre, Virginie  |e verfasserin  |4 aut 
700 1 |a Meile, Jean-Christophe  |e verfasserin  |4 aut 
700 1 |a Payet, Jim  |e verfasserin  |4 aut 
700 1 |a Conéjéro, Geneviève  |e verfasserin  |4 aut 
700 1 |a Costet, Laurent  |e verfasserin  |4 aut 
700 1 |a Fock-Bastide, Isabelle  |e verfasserin  |4 aut 
700 1 |a Joët, Thierry  |e verfasserin  |4 aut 
700 1 |a Dussert, Stéphane  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Plant physiology and biochemistry : PPB  |d 1991  |g 194(2023) vom: 01. Jan., Seite 627-637  |w (DE-627)NLM098178261  |x 1873-2690  |7 nnns 
773 1 8 |g volume:194  |g year:2023  |g day:01  |g month:01  |g pages:627-637 
856 4 0 |u http://dx.doi.org/10.1016/j.plaphy.2022.12.013  |3 Volltext 
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