Adenovirus vector system : construction, history and therapeutic applications

Since the isolation of adenovirus (AdV) in 1953, AdVs have been used as vectors for various therapeutic purposes, such as gene therapy in cancers and other malignancies, vaccine development and delivery of CRISPR-Cas9 machinery. Over the years, several AdV vector modifications have been introduced,...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:BioTechniques. - 1988. - 73(2022), 6 vom: 21. Dez., Seite 297-305
1. Verfasser: Syyam, Anum (VerfasserIn)
Weitere Verfasser: Nawaz, Amjad, Ijaz, Aroosa, Sajjad, Umar, Fazil, Anila, Irfan, Sofia, Muzaffar, Aleeha, Shahid, Muhammad, Idrees, Muhammad, Malik, Kausar, Afzal, Samia
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2022
Zugriff auf das übergeordnete Werk:BioTechniques
Schlagworte:Journal Article Review Ad5 AdV AdV modification AdV tropism CRISPR-Cas9 Cre-lox method adenovirus vectors gene therapy mehr... homologous recombination vaccine development