On the Influence of Nucleic Acid Backbone Modifications on Lipid Nanoparticle Morphology
Nucleic acid therapeutics represent a major advance toward treating diseases at their root cause. However, nucleic acids are prone to degradation by serum endonucleases, clearance through the immune system, and rapid degradation in complex medium. To overcome these barriers, nucleic acids frequently...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1992. - 38(2022), 46 vom: 22. Nov., Seite 14036-14043
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| 1. Verfasser: |
An, Kevin
(VerfasserIn) |
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| Weitere Verfasser: |
Kurek, Daniel,
Mahadeo, Mark,
Zhang, Yao,
Thewalt, Jenifer L,
Cullis, Pieter R,
Kulkarni, Jayesh A |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2022
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| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Lipid Nanoparticles
Nucleic Acids
Liposomes
RNA, Small Interfering |
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