Development of Drug Carriers with Biocompatibility Based On Human Serum Albumin and β-Cyclodextrin Molecules and Study of Anticancer Activity

Herein, a novel molecule S4, which could form a uniform S4 spherical aggregate in water, was synthesized, and the S4 aggregate was used to load Dox to prepare the S4Dox nanomedicine. The loading efficiency was 80.0 ± 4.5%. The pH response and slow release of Dox were the typical characteristics of t...

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Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 38(2022), 45 vom: 15. Nov., Seite 13686-13696
Auteur principal: Yan, Miaomiao (Auteur)
Autres auteurs: Li, Jing, Gu, Xiulian, Hou, Xinyi, Ma, Yue, Cui, Haoyu, Feng, Chuanxing, Ma, Liying, Wei, Guangcheng
Format: Article en ligne
Langue:English
Publié: 2022
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article Research Support, Non-U.S. Gov't Drug Carriers Doxorubicin 80168379AG Serum Albumin, Human ZIF514RVZR beta-Cyclodextrins