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231226s2022 xx |||||o 00| ||eng c |
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|a 10.1007/s10646-022-02601-y
|2 doi
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|a pubmed24n1160.xml
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|a (DE-627)NLM348157622
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|a (NLM)36301371
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|a DE-627
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|e rakwb
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|a eng
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| 100 |
1 |
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|a Ghasemi, Vahid
|e verfasserin
|4 aut
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| 245 |
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|a Toxic evaluation of Proclaim Fit® on adult and larval worker honey bees
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|c 2022
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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|a Date Completed 15.11.2022
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|a Date Revised 15.11.2022
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
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|a Impacts to honey bees due to exposure to agricultural pesticides is one of the most serious threats to the beekeeping industry. Our research evaluated toxicity of the formulated insecticides Lufenuron+Emamectin benzoate (Proclaim Fit®) on the European honey bee Apis mellifera L. at field-realistic concentration (worst-case scenario). Newly emerged (≤24-h old) and forager (unknown age) worker bees were treated with the field recommended concentration of Proclaim Fit® using three routes of exposure including residual contact, oral, and spray within the laboratory. We also assessed the effects of Proclaim Fit® on the specific activity of some well-known detoxifying enzymes including α-esterase, β-esterase, and Glutathione S-transferase (GST) in the honey bees. In addition, toxicity of the formulation was tested on 4th instar larvae within the hive. Based on estimated median survival times (MSTs), Proclaim Fit® was highly toxic to the bees, especially when applied as spray. According to our estimated relative median potency (RMP) values, newly emerged bees were 1.72× more susceptible than foragers to Proclaim Fit® applied orally. Enzyme assays revealed the considerable involvement of the enzymes, especially GST and α-esterase, in detoxification of the Proclaim Fit®, but their activities were significantly influenced by route of exposure and age of bee. Notably, Proclaim Fit® was highly toxic to 4th instar honey bee larvae. Our results generally indicate a potent toxicity of Proclaim Fit® toward honey bees. Therefore, its application requires serious consideration and adherence to strict guidelines, especially during the flowering time of crops
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|a Journal Article
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|a Apis mellifera
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|a Detoxifying enzymes
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|a Field-realistic concentration
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|a Lufenuron+Emamectin benzoate
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|a Median survival time
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|a Relative median potency
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|a Insecticides
|2 NLM
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|a Pesticides
|2 NLM
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|a Glutathione Transferase
|2 NLM
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|a EC 2.5.1.18
|2 NLM
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|a Esterases
|2 NLM
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|a EC 3.1.-
|2 NLM
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1 |
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|a Salehinejad, Ali
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Ghadamyari, Mohammad
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Jack, Cameron J
|e verfasserin
|4 aut
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|a Sharifi, Mahboobeh
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Ecotoxicology (London, England)
|d 1992
|g 31(2022), 9 vom: 27. Nov., Seite 1441-1449
|w (DE-627)NLM098212214
|x 1573-3017
|7 nnns
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|g volume:31
|g year:2022
|g number:9
|g day:27
|g month:11
|g pages:1441-1449
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|u http://dx.doi.org/10.1007/s10646-022-02601-y
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