Are mutations usually deleterious? A perspective on the fitness effects of mutation accumulation

All adaptive alleles in existence today began as mutations, but a common view in ecology, evolution, and genetics is that non-neutral mutations are much more likely to be deleterious than beneficial and will be removed by purifying selection. By dramatically limiting the effectiveness of selection i...

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Veröffentlicht in:Evolutionary ecology. - 1998. - 36(2022), 5 vom: 29. Okt., Seite 753-766
1. Verfasser: Bao, Kevin (VerfasserIn)
Weitere Verfasser: Melde, Robert H, Sharp, Nathaniel P
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2022
Zugriff auf das übergeordnete Werk:Evolutionary ecology
Schlagworte:Journal Article Distribution of fitness effects beneficial mutations fitness landscape life history traits