Rapid evolution of an RNA virus to escape recognition by a rice nucleotide-binding and leucine-rich repeat domain immune receptor

Rapid evolution of an RNA virus to escape recognition by a rice nucleotide-binding and leucine-rich repeat domain immune receptor

© 2022 The Authors. New Phytologist © 2022 New Phytologist Foundation.

Détails bibliographiques
Publié dans:The New phytologist. - 1984. - 237(2023), 3 vom: 30. Feb., Seite 900-913
Auteur principal: Bonnamy, Mélia (Auteur)
Autres auteurs: Pinel-Galzi, Agnès, Gorgues, Lucille, Chalvon, Véronique, Hébrard, Eugénie, Chéron, Sophie, Nguyen, Tràng Hiếu, Poulicard, Nils, Sabot, François, Pidon, Hélène, Champion, Antony, Césari, Stella, Kroj, Thomas, Albar, Laurence
Format: Article en ligne
Langue:English
Publié: 2023
Accès à la collection:The New phytologist
Sujets:Journal Article Research Support, Non-U.S. Gov't evolution immune receptor nucleotide-binding and leucine-rich immune receptor (NLR) resistance breakdown rice rice yellow mottle virus virus disease resistance Leucine plus... GMW67QNF9C Nucleotides Plant Proteins NLR Proteins
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520 |a Viral diseases are a major limitation for crop production, and their control is crucial for sustainable food supply. We investigated by a combination of functional genetics and experimental evolution the resistance of rice to the rice yellow mottle virus (RYMV), which is among the most devastating rice pathogens in Africa, and the mechanisms underlying the extremely fast adaptation of the virus to its host. We found that the RYMV3 gene that protects rice against the virus codes for a nucleotide-binding and leucine-rich repeat domain immune receptor (NLRs) from the Mla-like clade of NLRs. RYMV3 detects the virus by forming a recognition complex with the viral coat protein (CP). The virus escapes efficiently from detection by mutations in its CP, some of which interfere with the formation of the recognition complex. This study establishes that NLRs also confer in monocotyledonous plants immunity to viruses, and reveals an unexpected functional diversity for NLRs of the Mla clade that were previously only known as fungal disease resistance proteins. In addition, it provides precise insight into the mechanisms by which viruses adapt to plant immunity and gives important knowledge for the development of sustainable resistance against viral diseases of cereals 
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650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a evolution 
650 4 |a immune receptor 
650 4 |a nucleotide-binding and leucine-rich immune receptor (NLR) 
650 4 |a resistance breakdown 
650 4 |a rice 
650 4 |a rice yellow mottle virus 
650 4 |a virus disease resistance 
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700 1 |a Pinel-Galzi, Agnès  |e verfasserin  |4 aut 
700 1 |a Gorgues, Lucille  |e verfasserin  |4 aut 
700 1 |a Chalvon, Véronique  |e verfasserin  |4 aut 
700 1 |a Hébrard, Eugénie  |e verfasserin  |4 aut 
700 1 |a Chéron, Sophie  |e verfasserin  |4 aut 
700 1 |a Nguyen, Tràng Hiếu  |e verfasserin  |4 aut 
700 1 |a Poulicard, Nils  |e verfasserin  |4 aut 
700 1 |a Sabot, François  |e verfasserin  |4 aut 
700 1 |a Pidon, Hélène  |e verfasserin  |4 aut 
700 1 |a Champion, Antony  |e verfasserin  |4 aut 
700 1 |a Césari, Stella  |e verfasserin  |4 aut 
700 1 |a Kroj, Thomas  |e verfasserin  |4 aut 
700 1 |a Albar, Laurence  |e verfasserin  |4 aut 
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