Transplantation to save the life, TSH screening to save the brain A report and brief literature review of autoimmune thyroid disease after HSCT for severe combined immunodeficiency

Transplantation to save the life, TSH screening to save the brain : A report and brief literature review of autoimmune thyroid disease after HSCT for severe combined immunodeficiency

Copyright © 2022. Published by Elsevier Inc.

Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 245(2022) vom: 29. Dez., Seite 109142
1. Verfasser: Baccelli, F (VerfasserIn)
Weitere Verfasser: Ortolano, R, Conti, F, Soncini, E, Baronio, F, Masetti, R, Ferrari, S, Cassio, A, Pession, A
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2022
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Case Reports Journal Article Review Autoimmunity Hematopoietic stem cells transplantation Infant Severe combined immunodeficiency Thyroid Thyrotropin 9002-71-5
Beschreibung
Zusammenfassung:Copyright © 2022. Published by Elsevier Inc.
Autoimmune thyroid disease has been described as a complication of HSCT for different indications and as a manifestation of inborn errors of immunity, like SCID. A 1-month female was diagnosed with RAG1-mutated SCID and received allogenic HSCT. She developed autoimmune hypothyroidism 5 months after transplantation and was treated with levo-thyroxine with a good response. Autoimmune thyroid disease can develop after HSCT during the immune reconstitution phase, leading to potentially severe neurological and growth impairment, particularly in SCID patients, often transplanted during the first year of life. Recommendations regarding early and frequent vigilance for thyroid function are needed in these patients
Beschreibung:Date Completed 28.11.2022
Date Revised 26.12.2022
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-7035
DOI:10.1016/j.clim.2022.109142