Colorimetric Biosensors Based on Polymer/Gold Hybrid Nanoparticles : Topological Effects of the Polymer Coating

Gold nanoparticles decorated with analyte recognition units can form the basis of colorimetric (bio)sensors. The presentation of those recognition units may play a critical role in determining sensor sensitivity. Herein, we use a model system to investigate the effect of the architecture of a polyme...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 38(2022), 40 vom: 11. Okt., Seite 12325-12332
1. Verfasser: Wang, Ruosong (VerfasserIn)
Weitere Verfasser: Schirmer, Lucas, Wieduwilt, Torsten, Förster, Ronny, Schmidt, Markus A, Freudenberg, Uwe, Werner, Carsten, Fery, Andreas, Rossner, Christian
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2022
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Polymers Gold 7440-57-5
LEADER 01000naa a22002652 4500
001 NLM346704006
003 DE-627
005 20231226032106.0
007 cr uuu---uuuuu
008 231226s2022 xx |||||o 00| ||eng c
024 7 |a 10.1021/acs.langmuir.2c02013  |2 doi 
028 5 2 |a pubmed24n1155.xml 
035 |a (DE-627)NLM346704006 
035 |a (NLM)36154138 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Wang, Ruosong  |e verfasserin  |4 aut 
245 1 0 |a Colorimetric Biosensors Based on Polymer/Gold Hybrid Nanoparticles  |b Topological Effects of the Polymer Coating 
264 1 |c 2022 
336 |a Text  |b txt  |2 rdacontent 
337 |a ƒaComputermedien  |b c  |2 rdamedia 
338 |a ƒa Online-Ressource  |b cr  |2 rdacarrier 
500 |a Date Completed 12.10.2022 
500 |a Date Revised 13.10.2022 
500 |a published: Print-Electronic 
500 |a Citation Status MEDLINE 
520 |a Gold nanoparticles decorated with analyte recognition units can form the basis of colorimetric (bio)sensors. The presentation of those recognition units may play a critical role in determining sensor sensitivity. Herein, we use a model system to investigate the effect of the architecture of a polymeric linker that connects gold nanoparticles with the recognition units. Our results show that the number of the latter that can be adsorbed during the assembly of the colorimetric sensors depends on the linker topology. We also show that this may lead to substantial differences in colorimetric sensor performance, particularly in situations in which the interactions with the analyte are comparably weak. Finally, we discuss design principles for efficient colorimetric sensor materials based on our findings 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 7 |a Polymers  |2 NLM 
650 7 |a Gold  |2 NLM 
650 7 |a 7440-57-5  |2 NLM 
700 1 |a Schirmer, Lucas  |e verfasserin  |4 aut 
700 1 |a Wieduwilt, Torsten  |e verfasserin  |4 aut 
700 1 |a Förster, Ronny  |e verfasserin  |4 aut 
700 1 |a Schmidt, Markus A  |e verfasserin  |4 aut 
700 1 |a Freudenberg, Uwe  |e verfasserin  |4 aut 
700 1 |a Werner, Carsten  |e verfasserin  |4 aut 
700 1 |a Fery, Andreas  |e verfasserin  |4 aut 
700 1 |a Rossner, Christian  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Langmuir : the ACS journal of surfaces and colloids  |d 1992  |g 38(2022), 40 vom: 11. Okt., Seite 12325-12332  |w (DE-627)NLM098181009  |x 1520-5827  |7 nnns 
773 1 8 |g volume:38  |g year:2022  |g number:40  |g day:11  |g month:10  |g pages:12325-12332 
856 4 0 |u http://dx.doi.org/10.1021/acs.langmuir.2c02013  |3 Volltext 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_22 
912 |a GBV_ILN_350 
912 |a GBV_ILN_721 
951 |a AR 
952 |d 38  |j 2022  |e 40  |b 11  |c 10  |h 12325-12332