New data analysis for BioSAXS at the ESRF
open access.
| Veröffentlicht in: | Journal of synchrotron radiation. - 1994. - 29(2022), Pt 5 vom: 01. Sept., Seite 1318-1328 |
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| 1. Verfasser: | |
| Weitere Verfasser: | , , , , , |
| Format: | Online-Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
2022
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| Zugriff auf das übergeordnete Werk: | Journal of synchrotron radiation |
| Schlagworte: | Journal Article BioSAXS automation biological small-angle X-ray scattering high brilliance high-throughput SAXS online data analysis online purification proteins size-exclusion chromatography mehr... |
| Zusammenfassung: | open access. The second phase of the ESRF upgrade program did not only provide a new storage ring (Extremely Brilliant Source, EBS) but also allowed several beamlines to be refurbished. The BioSAXS beamline (located on port BM29) was upgraded with a new wiggler source and a larger detector. All analysis software has been rewritten to cope with the increased data flux and continues to provide beamline users with reduced and pre-processed data in real time. This article describes FreeSAS, an open-source collection of various small-angle scattering analysis algorithms needed to reduce and analyze BioSAXS data, and Dahu, the tool used to interface data analysis with beamline control. It further presents the data-processing pipelines for the different data acquisitions modes of the beamline, using either a sample changer for individual homogeneous samples or an inline size-exclusion chromatography setup |
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| Beschreibung: | Date Completed 09.09.2022 Date Revised 04.09.2024 published: Print-Electronic Citation Status MEDLINE |
| ISSN: | 1600-5775 |
| DOI: | 10.1107/S1600577522007238 |