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|a 10.14989/ActaUrolJap_68_8_277
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|a Sugino, Fumiya
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|a Paratesticular Low-Grade Fibromyxoid Sarcoma
|b A Case Report
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|c 2022
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|a Date Completed 09.09.2022
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|a Date Revised 09.09.2022
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|a published: Print
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|a Citation Status MEDLINE
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|a A 36-year-old man presented with painless swelling in the right side scrotum. Ultrasonography showed a hypoechoic tumor with mosaic pattern. Plain computed tomograghy (CT) revealed a 67 mm scrotal cystic lesion with low density area. We suspected an intrascrotal tumor and performed right side radical orchiectomy. The removed sample was yellow clear and elastic hard. A 7 cm multilocular cystic tumor was present on the head side of the normal testis. The cut-surface and the contents of the mass revealed a jelly-like viscous liquid. On the microscopic examination, the tumor was composed of mucinous stroma and spindle-shaped atypical cells with hyperchromatic oval nuclei and eosinophilic cytoplasm. There was a characteristic network of blood vessesls with hyperhyalinization in the myxoid zones. Immunohistochemically, CDK4, MDM2, AE1/AE3, S-100, Alpha-SMA and desmin were negative, but MUC4 showed focal cytoplasmic positivity in the neoplastic cells. In the reverse transcription polymerase chain reaction assay, no FUS-CREB3L2/FUS-CREB3L1 fusion transcripts were identified although the detectable messages of the housekeeping genes were noted. The tumour was finally diagnosed as a paratesticular low-grade fibromyxoid sarcoma. Postoperative course was uneventful and no recurrence or metastasis was seen four months after the operation
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|a Tamaki, Masayoshi
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|a Komeda, Hisao
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|a Watanabe, Naoki
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|a Tanaka, Takuji
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|i Enthalten in
|t Hinyokika kiyo. Acta urologica Japonica
|d 1962
|g 68(2022), 8 vom: 21. Aug., Seite 277-280
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|g volume:68
|g year:2022
|g number:8
|g day:21
|g month:08
|g pages:277-280
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