SnRK1A-mediated phosphorylation of a cytosolic ATPase positively regulates rice innate immunity and is inhibited by Ustilaginoidea virens effector SCRE1

SnRK1A-mediated phosphorylation of a cytosolic ATPase positively regulates rice innate immunity and is inhibited by Ustilaginoidea virens effector SCRE1

© 2022 The Authors. New Phytologist © 2022 New Phytologist Foundation.

Bibliographische Detailangaben
Veröffentlicht in:The New phytologist. - 1984. - 236(2022), 4 vom: 04. Nov., Seite 1422-1440
1. Verfasser: Yang, Jiyun (VerfasserIn)
Weitere Verfasser: Zhang, Nan, Wang, Jiyang, Fang, Anfei, Fan, Jing, Li, Dayong, Li, Yuejiao, Wang, Shanzhi, Cui, Fuhao, Yu, Junjie, Liu, Yongfeng, Wang, Wen-Ming, Peng, You-Liang, He, Sheng Yang, Sun, Wenxian
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2022
Zugriff auf das übergeordnete Werk:The New phytologist
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Oryza sativa Ustilaginoidea virens XA21-binding protein 24 cytosolic ATPase rice innate immunity small cysteine-rich effector 1 sucrose nonfermenting-1-related protein kinase 1 Adenosine Triphosphatases mehr... EC 3.6.1.- Pathogen-Associated Molecular Pattern Molecules Chitin 1398-61-4 Adenosine Triphosphate 8L70Q75FXE
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520 |a © 2022 The Authors. New Phytologist © 2022 New Phytologist Foundation. 
520 |a Rice false smut caused by Ustilaginoidea virens is becoming one of the most recalcitrant rice diseases worldwide. However, the molecular mechanisms underlying rice immunity against U. virens remain unknown. Using genetic, biochemical and disease resistance assays, we demonstrated that the xb24 knockout lines generated in non-Xa21 rice background exhibit an enhanced susceptibility to the fungal pathogens U. virens and Magnaporthe oryzae. Consistently, flg22- and chitin-induced oxidative burst and expression of pathogenesis-related genes in the xb24 knockout lines were greatly attenuated. As a central mediator of energy signaling, SnRK1A interacts with and phosphorylates XB24 at Thr83 residue to promote ATPase activity. SnRK1A is activated by pathogen-associated molecular patterns and positively regulates plant immune responses and disease resistance. Furthermore, the virulence effector SCRE1 in U. virens targets host ATPase XB24. The interaction inhibits ATPase activity of XB24 by blocking ATP binding to XB24. Meanwhile, SCRE1 outcompetes SnRK1A for XB24 binding, and thereby suppresses SnRK1A-mediated phosphorylation and ATPase activity of XB24. Our results indicate that the conserved SnRK1A-XB24 module in multiple crop plants positively contributes to plant immunity and uncover an unidentified molecular strategy to promote infection in U. virens and a novel host target in fungal pathogenesis 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a Oryza sativa 
650 4 |a Ustilaginoidea virens 
650 4 |a XA21-binding protein 24 
650 4 |a cytosolic ATPase 
650 4 |a rice innate immunity 
650 4 |a small cysteine-rich effector 1 
650 4 |a sucrose nonfermenting-1-related protein kinase 1 
650 7 |a Adenosine Triphosphatases  |2 NLM 
650 7 |a EC 3.6.1.-  |2 NLM 
650 7 |a Pathogen-Associated Molecular Pattern Molecules  |2 NLM 
650 7 |a Chitin  |2 NLM 
650 7 |a 1398-61-4  |2 NLM 
650 7 |a Adenosine Triphosphate  |2 NLM 
650 7 |a 8L70Q75FXE  |2 NLM 
700 1 |a Zhang, Nan  |e verfasserin  |4 aut 
700 1 |a Wang, Jiyang  |e verfasserin  |4 aut 
700 1 |a Fang, Anfei  |e verfasserin  |4 aut 
700 1 |a Fan, Jing  |e verfasserin  |4 aut 
700 1 |a Li, Dayong  |e verfasserin  |4 aut 
700 1 |a Li, Yuejiao  |e verfasserin  |4 aut 
700 1 |a Wang, Shanzhi  |e verfasserin  |4 aut 
700 1 |a Cui, Fuhao  |e verfasserin  |4 aut 
700 1 |a Yu, Junjie  |e verfasserin  |4 aut 
700 1 |a Liu, Yongfeng  |e verfasserin  |4 aut 
700 1 |a Wang, Wen-Ming  |e verfasserin  |4 aut 
700 1 |a Peng, You-Liang  |e verfasserin  |4 aut 
700 1 |a He, Sheng Yang  |e verfasserin  |4 aut 
700 1 |a Sun, Wenxian  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t The New phytologist  |d 1984  |g 236(2022), 4 vom: 04. Nov., Seite 1422-1440  |w (DE-627)NLM09818248X  |x 1469-8137  |7 nnas 
773 1 8 |g volume:236  |g year:2022  |g number:4  |g day:04  |g month:11  |g pages:1422-1440 
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