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231226s2022 xx |||||o 00| ||eng c |
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|a 10.1021/acs.langmuir.2c01658
|2 doi
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|a pubmed24n1150.xml
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|a (NLM)35984448
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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|a Chang, Yu
|e verfasserin
|4 aut
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|a On-Demand Fully Enclosed Superhydrophobic-Optofluidic Devices Enabled by Microstereolithography
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|c 2022
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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|a Date Completed 31.08.2022
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|a Date Revised 31.08.2023
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Superhydrophobic surface-based optofluidics have been introduced to biosensors and unconventional optics with unique advantages, such as low light loss and power consumption. However, most of these platforms were made with planar-like microstructures and nanostructures, which may cause bonding issues and result in significant waveguide loss. Here, we introduce a fully enclosed superhydrophobic-based optofluidics system, enabled by a one-step microstereolithography procedure. Various microstructured cladding designs with a feature size down to 100 μm were studied and a "T-type" overhang design exhibits the lowest optical loss, regardless of the excitation wavelength. Surprisingly, the optical loss of superhydrophobic-based optofluidics is not solely decided by the solid area fraction at the solid/water/air interface, but also the cross-section shape and the effective cladding layer composition. We show that this fully enclosed optofluidic system can be used for CRISPR-labeled quantum dot quantification, intended for in vitro and in vivo CRISPR therapeutics
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|a Journal Article
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|a Research Support, N.I.H., Extramural
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|a Research Support, Non-U.S. Gov't
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|a Bao, Mengdi
|e verfasserin
|4 aut
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|a Waitkus, Jacob
|e verfasserin
|4 aut
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|a Cai, Haogang
|e verfasserin
|4 aut
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|a Du, Ke
|e verfasserin
|4 aut
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 38(2022), 34 vom: 30. Aug., Seite 10672-10678
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
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|g volume:38
|g year:2022
|g number:34
|g day:30
|g month:08
|g pages:10672-10678
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|u http://dx.doi.org/10.1021/acs.langmuir.2c01658
|3 Volltext
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|d 38
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