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231226s2022 xx |||||o 00| ||eng c |
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|a 10.1021/acs.langmuir.2c00937
|2 doi
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|a pubmed24n1146.xml
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|a (DE-627)NLM344004376
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|a (NLM)35880575
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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|a Soto-Cruz, Jackeline
|e verfasserin
|4 aut
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|a Polysaccharide/Lipid Nanoconjugates as Alternative Building Blocks for Highly Biocompatible Microcapsules
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|c 2022
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Completed 10.08.2022
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|a Date Revised 29.08.2022
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Saccharide/lipid nanoconjugates are attractive building blocks for the construction of micro- and nanosized structures because of the roles of glycolipids in human body, courtesy of their intrinsic and functional properties. Herein, nanoconjugates based on dextran and oleic acid (Dex-OA) were synthesized via facile amide-linkage chemistry. The resultant Dex-OA micelles could self-assemble into spherical water-filled microcapsules via a water-in-oil emulsification process. By cross-linking, the microcapsules could be transferred to aqueous media, forming a stable microcapsule dispersion. According to optical and fluorescence microscopy, the microcapsules displayed a spherical morphology, and their synthesis is dependent on the concentration of Dex-OA nanoconjugates. Furthermore, the microcapsules could easily encapsulate and retain fluorescently labeled dextran. This strategy offers a robust and efficient method for the construction of microcapsules from fully natural amphiphilic building blocks with the potential for application in diverse fields such as biomedicine, protocell research, and microreactors
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Capsules
|2 NLM
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|a Dextrans
|2 NLM
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|a Lipids
|2 NLM
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|a Nanoconjugates
|2 NLM
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|a Water
|2 NLM
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|a 059QF0KO0R
|2 NLM
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|a Mukwaya, Vincent
|e verfasserin
|4 aut
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|a Naz, Mehwish
|e verfasserin
|4 aut
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|a Zhang, Peipei
|e verfasserin
|4 aut
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|a López-Brenes, María José
|e verfasserin
|4 aut
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|a Sáenz-Arce, Giovanni
|e verfasserin
|4 aut
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|a Rojas-Carrillo, Oscar
|e verfasserin
|4 aut
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|a Dou, Hongjing
|e verfasserin
|4 aut
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1999
|g 38(2022), 31 vom: 09. Aug., Seite 9556-9566
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
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|g volume:38
|g year:2022
|g number:31
|g day:09
|g month:08
|g pages:9556-9566
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|u http://dx.doi.org/10.1021/acs.langmuir.2c00937
|3 Volltext
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