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231226s2022 xx |||||o 00| ||eng c |
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|a 10.1093/jxb/erac267
|2 doi
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|a pubmed24n1143.xml
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|a (DE-627)NLM342917153
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|a (NLM)35770874
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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1 |
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|a Scarpin, M Regina
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Translating across kingdoms
|b target of rapamycin promotes protein synthesis through conserved and divergent pathways in plants
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|c 2022
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Completed 21.11.2022
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|a Date Revised 02.07.2023
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|a published: Print
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|a Citation Status MEDLINE
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|a © The Author(s) 2022. Published by Oxford University Press on behalf of the Society for Experimental Biology. All rights reserved. For permissions, please email: journals.permissionsoup.com.
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|a mRNA translation is the growth rate-limiting step in genome expression. Target of rapamycin (TOR) evolved a central regulatory role in eukaryotes as a signaling hub that monitors nutrient availability to maintain homeostasis and promote growth, largely by increasing the rate of translation initiation and protein synthesis. The dynamic pathways engaged by TOR to regulate translation remain debated even in well-studied yeast and mammalian models, however, despite decades of intense investigation. Recent studies have firmly established that TOR also regulates mRNA translation in plants through conserved mechanisms, such as the TOR-LARP1-5'TOP signaling axis, and through pathways specific to plants. Here, we review recent advances in our understanding of the regulation of mRNA translation in plants by TOR
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|a Review
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|a Journal Article
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|a Research Support, N.I.H., Extramural
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|a Arabidopsis thaliana
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|a 5ʹTOP motifs
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|a LARP1
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|a TOR
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|a evolution
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|a kinase signaling
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|a protein synthesis
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|a ribosomes
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|a target of rapamycin
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| 650 |
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|a translation
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|a RNA, Messenger
|2 NLM
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| 650 |
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|a Sirolimus
|2 NLM
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| 650 |
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|a W36ZG6FT64
|2 NLM
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| 700 |
1 |
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|a Simmons, Carl H
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Brunkard, Jacob O
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Journal of experimental botany
|d 1985
|g 73(2022), 20 vom: 15. Nov., Seite 7016-7025
|w (DE-627)NLM098182706
|x 1460-2431
|7 nnns
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| 773 |
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|g volume:73
|g year:2022
|g number:20
|g day:15
|g month:11
|g pages:7016-7025
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|u http://dx.doi.org/10.1093/jxb/erac267
|3 Volltext
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|d 73
|j 2022
|e 20
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|h 7016-7025
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