Chemical biology to dissect molecular mechanisms underlying plant circadian clocks

© 2022 The Authors. New Phytologist © 2022 New Phytologist Foundation.

Bibliographische Detailangaben
Veröffentlicht in:The New phytologist. - 1979. - 235(2022), 4 vom: 06. Aug., Seite 1336-1343
1. Verfasser: Nakamichi, Norihito (VerfasserIn)
Weitere Verfasser: Yamaguchi, Junichiro, Sato, Ayato, Fujimoto, Kazuhiro J, Ota, Eisuke
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2022
Zugriff auf das übergeordnete Werk:The New phytologist
Schlagworte:Journal Article Review Research Support, Non-U.S. Gov't Arabidopsis thaliana chemical biology chemical screening circadian clock small molecule target identification Arabidopsis Proteins
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520 |a Circadian clocks regulate the diel rhythmic physiological activities of plants, enabling them to anticipate and adapt to day-night and seasonal changes. Genetic and biochemical approaches have suggested that transcription-translation feedback loops (TTFL) are crucial for Arabidopsis clock function. Recently, the study of chemical chronobiology has emerged as a discipline within the circadian clock field, with important and complementary discoveries from both plant and animal research. In this review, we introduce recent advances in chemical biology using small molecules to perturb plant circadian clock function through TTFL components. Studies using small molecule clock modulators have been instrumental for revealing the role of post-translational modification in the clock, or the metabolite-dependent clock input pathway, as well as for controlling clock-dependent flowering time 
650 4 |a Journal Article 
650 4 |a Review 
650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a Arabidopsis thaliana 
650 4 |a chemical biology 
650 4 |a chemical screening 
650 4 |a circadian clock 
650 4 |a small molecule 
650 4 |a target identification 
650 7 |a Arabidopsis Proteins  |2 NLM 
700 1 |a Yamaguchi, Junichiro  |e verfasserin  |4 aut 
700 1 |a Sato, Ayato  |e verfasserin  |4 aut 
700 1 |a Fujimoto, Kazuhiro J  |e verfasserin  |4 aut 
700 1 |a Ota, Eisuke  |e verfasserin  |4 aut 
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