Implant Insertion Procedure of the Port Delivery System With Ranibizumab Overview and Clinical Pearls

Implant Insertion Procedure of the Port Delivery System With Ranibizumab : Overview and Clinical Pearls

OBJECTIVE: To describe the Port Delivery System with ranibizumab implant insertion procedure

Bibliographische Detailangaben
Veröffentlicht in:Ophthalmic surgery, lasers & imaging retina. - 2013. - 53(2022), 5 vom: 29. Mai, Seite 249-256
1. Verfasser: Pieramici, Dante J (VerfasserIn)
Weitere Verfasser: Wieland, Mark R, Stewart, Jay M, Chang, Robert T, Gune, Shamika A, Malhotra, Varun K, Barteselli, Giulio, Awh, Carl C
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2022
Zugriff auf das übergeordnete Werk:Ophthalmic surgery, lasers & imaging retina
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Ranibizumab ZL1R02VT79
Beschreibung
Zusammenfassung:OBJECTIVE: To describe the Port Delivery System with ranibizumab implant insertion procedure
METHODS: A surgical procedure based on the clinical trial program in patients with retinal diseases
RESULTS: An infusion line is placed in the infero-temporal quadrant; a superotemporal quadrant corneal traction suture is recommended. The superotemporal quadrant peritomy of 6 × 6 mm is executed with gentle, purposeful tissue handling. Generous posterior and lateral sub-Tenon's capsule dissection creates laxity for the subsequent closure. Adequate scleral hemostasis is achieved with wet-field cautery to maintain a clean field. The implant is filled under magnification with a customized formulation of ranibizumab. A precise 3.5-mm-long scleral incision (4 mm posterior and parallel to the limbus) is created to ensure proper implant fit. The exposed pars plana undergoes laser ablation to reduce vitreous hemorrhage risk. A pars plana incision is made, and the implant is inserted perpendicular to the globe and seated flush against the sclera. Complete closure of both the conjunctiva and Tenon's capsule with scleral anchoring and mild tissue overhang at the anterior limbus is performed to reduce conjunctival erosion and retraction risks
CONCLUSION: The procedure is straightforward yet requires precise preoperative and intraoperative preparation and standardized surgical techniques. [Ophthalmic Surg Lasers Imaging Retina. 2022;53:249-256.]
Beschreibung:Date Completed 19.05.2022
Date Revised 20.05.2022
published: Print-Electronic
Citation Status MEDLINE
ISSN:2325-8179
DOI:10.3928/23258160-20220408-01