Anti-inflammatory and immune therapy in severe coronavirus disease 2019 (COVID-19) patients : An update

Copyright © 2022. Published by Elsevier Inc.

Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 239(2022) vom: 03. Juni, Seite 109022
1. Verfasser: Zhang, Wen (VerfasserIn)
Weitere Verfasser: Qin, Chenman, Fei, Yunyun, Shen, Min, Zhou, Yangzhong, Zhang, Yan, Zeng, Xiaofeng, Zhang, Shuyang
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2022
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Review Research Support, Non-U.S. Gov't Anti-inflammation treatment Coronavirus disease 2019 (COVID-19) Cytokine storm Immune therapy Anti-Inflammatory Agents Hydroxychloroquine 4QWG6N8QKH mehr... Chloroquine 886U3H6UFF
Beschreibung
Zusammenfassung:Copyright © 2022. Published by Elsevier Inc.
In March 2020, when coronavirus disease 2019 (COVID-19) was just beginning to spread around the world, we presented the potential benefits and controversies of anti-inflammatory therapy in COVID-19 patients based on the limited experience and proposed some types of anti-inflammatory drugs with potential therapeutic value, while without evidence-based data. In the past one more year, many clinical trials or real-world studies have been performed, either confirm or deny the efficacy of certain anti-inflammatory drugs in the treatment of COVID-19. In this review we summarize the progress of anti-inflammatory and immune therapy in COVID-19, including glucocorticoids, IL-6 antagonist, IL-1 inhibitor, kinase inhibitors, non-steroidal anti-inflammatory drugs and chloroquine/hydroxychloroquine
Beschreibung:Date Completed 02.06.2022
Date Revised 07.12.2022
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-7035
DOI:10.1016/j.clim.2022.109022