|
|
|
|
| LEADER |
01000naa a22002652 4500 |
| 001 |
NLM339991178 |
| 003 |
DE-627 |
| 005 |
20231226004134.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231226s2022 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1016/j.clim.2022.109021
|2 doi
|
| 028 |
5 |
2 |
|a pubmed24n1133.xml
|
| 035 |
|
|
|a (DE-627)NLM339991178
|
| 035 |
|
|
|a (NLM)35470063
|
| 035 |
|
|
|a (PII)S1521-6616(22)00102-4
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Lo, Mindy S
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a Concepts in lupus pathophysiology
|b Lessons learned from disease across the spectrum
|
| 264 |
|
1 |
|c 2022
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 17.05.2022
|
| 500 |
|
|
|a Date Revised 20.05.2022
|
| 500 |
|
|
|a published: Print-Electronic
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a Copyright © 2022 Elsevier Inc. All rights reserved.
|
| 520 |
|
|
|a Current understanding of the pathophysiology of systemic lupus erythematosus has expanded rapidly over the past few decades. These advances have been driven in part by advances in sequencing technology allowing better insights into the genetic underpinnings of the disease, but also by recognition that the inherent heterogeneity of lupus permits detailed study of various aspects of autoimmune physiology. This review outlines some of the lessons learned over time from the study of SLE across different age groups and different phenotypes
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a Review
|
| 650 |
|
4 |
|a Complement
|
| 650 |
|
4 |
|a Exome sequencing
|
| 650 |
|
4 |
|a Interferon
|
| 650 |
|
4 |
|a Lupus
|
| 650 |
|
4 |
|a Monogenic
|
| 650 |
|
4 |
|a Pathophysiology
|
| 650 |
|
4 |
|a Systemic lupus erythematosus
|
| 773 |
0 |
8 |
|i Enthalten in
|t Clinical immunology (Orlando, Fla.)
|d 1999
|g 238(2022) vom: 20. Mai, Seite 109021
|w (DE-627)NLM098196855
|x 1521-7035
|7 nnns
|
| 773 |
1 |
8 |
|g volume:238
|g year:2022
|g day:20
|g month:05
|g pages:109021
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1016/j.clim.2022.109021
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_11
|
| 912 |
|
|
|a GBV_ILN_24
|
| 912 |
|
|
|a GBV_ILN_350
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 238
|j 2022
|b 20
|c 05
|h 109021
|