Opfi : A Python package for identifying gene clusters in large genomics and metagenomics data sets

Gene clusters are sets of co-localized, often contiguous genes that together perform specific functions, many of which are relevant to biotechnology. There is a need for software tools that can extract candidate gene clusters from vast amounts of available genomic data. Therefore, we developed Opfi:...

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Bibliographische Detailangaben
Veröffentlicht in:Journal of open source software. - 2017. - 6(2021), 66 vom: 29.
1. Verfasser: Hill, Alexis M (VerfasserIn)
Weitere Verfasser: Rybarski, James R, Hu, Kuang, Finkelstein, Ilya J, Wilke, Claus O
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2021
Zugriff auf das übergeordnete Werk:Journal of open source software
Schlagworte:Journal Article
Beschreibung
Zusammenfassung:Gene clusters are sets of co-localized, often contiguous genes that together perform specific functions, many of which are relevant to biotechnology. There is a need for software tools that can extract candidate gene clusters from vast amounts of available genomic data. Therefore, we developed Opfi: a modular pipeline for identification of arbitrary gene clusters in assembled genomic or metagenomic sequences. Opfi contains functions for annotation, de-deduplication, and visualization of putative gene clusters. It utilizes a customizable rule-based filtering approach for selection of candidate systems that adhere to user-defined criteria. Opfi is implemented in Python, and is available on the Python Package Index and on Bioconda (Grüning et al., 2018)
Beschreibung:Date Revised 28.03.2023
published: Print-Electronic
Citation Status PubMed-not-MEDLINE
ISSN:2475-9066
DOI:10.21105/joss.03678