|
|
|
|
| LEADER |
01000naa a22002652 4500 |
| 001 |
NLM339149140 |
| 003 |
DE-627 |
| 005 |
20231226002247.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231226s2022 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1002/adma.202201051
|2 doi
|
| 028 |
5 |
2 |
|a pubmed24n1130.xml
|
| 035 |
|
|
|a (DE-627)NLM339149140
|
| 035 |
|
|
|a (NLM)35385160
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Wang, Jie
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a Intelligent Micro-/Nanorobots for Cancer Theragnostic
|
| 264 |
|
1 |
|c 2022
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 30.12.2022
|
| 500 |
|
|
|a Date Revised 03.01.2023
|
| 500 |
|
|
|a published: Print-Electronic
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a © 2022 Wiley-VCH GmbH.
|
| 520 |
|
|
|a Cancer is one of the most intractable diseases owing to its high mortality rate and lack of effective diagnostic and treatment tools. Advancements in micro-/nanorobot (MNR)-assisted sensing, imaging, and therapeutics offer unprecedented opportunities to develop MNR-based cancer theragnostic platforms. Unlike ordinary nanoparticles, which exhibit Brownian motion in biofluids, MNRs overcome viscous resistance in an ultralow Reynolds number (Re << 1) environment by effective self-propulsion. This unique locomotion property has motivated the advanced design and functionalization of MNRs as a basis for next-generation cancer-therapy platforms, which offer the potential for precise distribution and improved permeation of therapeutic agents. Enhanced barrier penetration, imaging-guided operation, and biosensing are additionally studied to enable the promising cancer-related applications of MNRs. Herein, the recent advances in MNR-based cancer therapy are comprehensively addresses, including actuation engines, diagnostics, medical imaging, and targeted drug delivery; promising research opportunities that can have a profound impact on cancer therapy over the next decade is highlighted
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a Review
|
| 650 |
|
4 |
|a drug delivery
|
| 650 |
|
4 |
|a medical imaging
|
| 650 |
|
4 |
|a micro-/nanorobotics
|
| 650 |
|
4 |
|a tumor diagnosis
|
| 650 |
|
4 |
|a tumor therapy
|
| 700 |
1 |
|
|a Dong, Yue
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Ma, Peng
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Wang, Yu
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Zhang, Fangyu
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Cai, Bocheng
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Chen, Peng
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Liu, Bi-Feng
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Advanced materials (Deerfield Beach, Fla.)
|d 1998
|g 34(2022), 52 vom: 30. Dez., Seite e2201051
|w (DE-627)NLM098206397
|x 1521-4095
|7 nnns
|
| 773 |
1 |
8 |
|g volume:34
|g year:2022
|g number:52
|g day:30
|g month:12
|g pages:e2201051
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1002/adma.202201051
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_350
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 34
|j 2022
|e 52
|b 30
|c 12
|h e2201051
|