Molecular Programming of NIR-IIb-Emissive Semiconducting Small Molecules for In Vivo High-Contrast Bioimaging Beyond 1500 nm

Molecular Programming of NIR-IIb-Emissive Semiconducting Small Molecules for In Vivo High-Contrast Bioimaging Beyond 1500 nm

© 2022 Wiley-VCH GmbH.

Détails bibliographiques
Publié dans:Advanced materials (Deerfield Beach, Fla.). - 1998. - 34(2022), 19 vom: 30. Mai, Seite e2201263
Auteur principal: Yuan, Yi (Auteur)
Autres auteurs: Feng, Zhe, Li, Shengliang, Huang, Zhongming, Wan, Yingpeng, Cao, Chen, Lin, Sien, Wu, Lan, Zhou, Jing, Liao, Liang-Sheng, Qian, Jun, Lee, Chun-Sing
Format: Article en ligne
Langue:English
Publié: 2022
Accès à la collection:Advanced materials (Deerfield Beach, Fla.)
Sujets:Journal Article NIR-II fluorescence imaging molecular programming nanoparticles semiconducting oligomers Fluorescent Dyes
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520 |a Materials with long-wavelength second near-infrared (NIR-II) emission are highly desired for in vivo dynamic visualizating of microstructures in deep tissues. Herein, by employing an atom-programming strategy, a series of highly fluorescent semiconducting oligomers (SOMs) with tunable NIR-IIb emissions are developed for bioimaging applications. After self-assembly into nanoparticles (NPs), they show good brightness, high photostability, and satisfactory biocompatibility. The SOM NPs are applied as probes for high-resolution imaging of whole-body and hind-limb blood vessels, biliary tract, and bladder with their emissions over 1500 nm. This work demonstrates an atom-programming strategy for constructing semiconducting small molecules with enhanced NIR-II fluorescence for deep-tissue imaging, affording new insight for advancing molecular design of NIR-II fluorophores 
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650 4 |a NIR-II 
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650 4 |a molecular programming 
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700 1 |a Feng, Zhe  |e verfasserin  |4 aut 
700 1 |a Li, Shengliang  |e verfasserin  |4 aut 
700 1 |a Huang, Zhongming  |e verfasserin  |4 aut 
700 1 |a Wan, Yingpeng  |e verfasserin  |4 aut 
700 1 |a Cao, Chen  |e verfasserin  |4 aut 
700 1 |a Lin, Sien  |e verfasserin  |4 aut 
700 1 |a Wu, Lan  |e verfasserin  |4 aut 
700 1 |a Zhou, Jing  |e verfasserin  |4 aut 
700 1 |a Liao, Liang-Sheng  |e verfasserin  |4 aut 
700 1 |a Qian, Jun  |e verfasserin  |4 aut 
700 1 |a Lee, Chun-Sing  |e verfasserin  |4 aut 
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