Cytotoxic T lymphocytes targeting a conserved SARS-CoV-2 spike epitope are efficient serial killers

Understanding immune response to infections and vaccines lags understanding humoral responses. While neutralizing antibody responses wane over time, T cells are instrumental in long-term immunity. We apply machine learning and time-lapse imaging microscopy in nanowell grids (TIMING) to study thousan...

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Bibliographische Detailangaben

Veröffentlicht in:	BioTechniques. - 1993. - 72(2022), 4 vom: 01. Apr., Seite 113-120
1. Verfasser:	Fathi, Mohsen (VerfasserIn)
Weitere Verfasser:	Charley, Lindsey, Cooper, Laurence Jn, Varadarajan, Navin, Meyer, Daniel D
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2022
Zugriff auf das übergeordnete Werk:	BioTechniques
Schlagworte:	Journal Article Research Support, Non-U.S. Gov't Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S. COVID-19 SARS-CoV-2 T cells cytokines cytotoxicity lymphocytes mehr... single-cell time-lapse imaging Antibodies, Viral COVID-19 Vaccines Epitopes Spike Glycoprotein, Coronavirus spike protein, SARS-CoV-2