Development of a Droplet Digital™ PCR DNA methylation detection and quantification assay of prenatal tobacco exposure
DNA methylation is a labile modification associated with gene expression control and environmental adaptations. High throughput, scalable and quantitative assessments of specific DNA methylation modifications in complex genomic regions for use in large population studies are needed. The performance...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | BioTechniques. - 1991. - 72(2022), 4 vom: 27. Apr., Seite 121-133
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| 1. Verfasser: |
Arroyo, Katti
(VerfasserIn) |
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| Weitere Verfasser: |
Nargizyan, Anahit,
Andrade, Francianne G,
Myint, Swe Swe,
Lu, Sabrina,
Pandey, Priyatama,
Yee, Amy,
de Smith, Adam J,
Wiemels, Joseph L |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2022
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| Zugriff auf das übergeordnete Werk: | BioTechniques
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
CpG dense regions
DNA methylation
Droplet Digital™ PCR (ddPCR™)
Illumina Infinium BeadChip array
Illumina MiSeq™ NGS system
bisulfite treatment
differentially methylated regions
gBlocks™ Gene Fragments
mehr...
neighboring CpGs
smoking biomarkers |
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